Evidence map›Paper›PMID 27583245›Full record

ReviewFrontiers in pediatrics2016

From Here to There, Progenitor Cells and Stem Cells Are Everywhere in Lung Vascular Remodeling.

Rebecca L Heise, Patrick A Link, Laszlo Farkas

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rebecca L HeiseDepartment of Biomedical Engineering, School of Engineering, Virginia Commonwealth University , Richmond, VA , USA.
Patrick A LinkDepartment of Biomedical Engineering, School of Engineering, Virginia Commonwealth University , Richmond, VA , USA.
Laszlo FarkasDepartment of Internal Medicine, Division of Pulmonary Disease and Critical Care Medicine, School of Medicine, Virginia Commonwealth University , Richmond, VA , USA.
Virginia Commonwealth University · US

Funding

Central role of endothelial stem cells in pulmonary arterial hypertensionR21HL123044 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI FARKAS, LASZLO, FREISHTAT, ROBERT J · 2016 to 2017
$454k
NHLBI NIH HHS R21 HL123044
6 · The paper itself

Abstract

The field of stem cell biology, cell therapy, and regenerative medicine has expanded almost exponentially, in the last decade. Clinical trials are evaluating the potential therapeutic use of stem cells in many adult and pediatric lung diseases with vascular component, such as bronchopulmonary dysplasia (BPD), chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), or pulmonary arterial hypertension (PAH). Extensive research activity is exploring the lung resident and circulating progenitor cells and their contribution to vascular complications of chronic lung diseases, and researchers hope to use resident or circulating stem/progenitor cells to treat chronic lung diseases and their vascular complications. It is becoming more and more clear that progress in mechanobiology will help to understand the various influences of physical forces and extracellular matrix composition on the phenotype and features of the progenitor cells and stem cells. The current review provides an overview of current concepts in the field.

Indexed as

bioengineeringcellularlung diseasesmechanotransductionpulmonary circulation/physiologystem cells

Identifiers

PMID27583245
PMCPMC4988064
OpenAlexW2507970930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.