ArticleActa radiologica open2016
Biparametric versus multiparametric MRI in the diagnosis of prostate cancer.
Article in Acta radiologica open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 37 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- A systematic review and meta-analysis of the diagnostic accuracy of biparametric prostate MRI for prostate cancer in men at risk.Prostate cancer and prostatic diseases · 2021Pooled it
- Diagnostic accuracy of highAging · 2021Pooled it
- Factors Influencing Variability in the Performance of Multiparametric Magnetic Resonance Imaging in Detecting Clinically Significant Prostate Cancer: A Systematic Literature Review.European urology oncology · 2020Pooled it
- The diagnostic accuracy of high b-value diffusion- and TAbdominal radiology (New York) · 2018Pooled it
- Bi- or multiparametric MRI in a sequential screening program for prostate cancer with PSA followed by MRI? Results from the Göteborg prostate cancer screening 2 trial.European radiology · 2021Trial
- A randomized trial of early detection of clinically significant prostate cancer (ProScreen): study design and rationale.European journal of epidemiology · 2017Trial
- Article
- AI-based detection of MRI-invisible prostate cancer with nnU-Net.The Canadian journal of urology · 2025Article
- Fast prostate MRI vs. conventional multiparametric prostate MRI: comparison and outcomes.Abdominal radiology (New York) · 2025Article
- Ultra-high gradient performance 3-Tesla MRI for super-fast and high-quality prostate imaging: initial experience.Insights into imaging · 2024Article
- Prostate cancer diagnosis based on multi-parametric MRI, clinical and pathological factors using deep learning.Scientific reports · 2024Article
- Dynamic Contrast-Enhanced Study in the mpMRI of the Prostate-Unnecessary or Underutilised? A Narrative Review.Diagnostics (Basel, Switzerland) · 2023Review
- Diagnostic performance of short noncontrast biparametric 3-T MRI for tonsillar infections: comparison with a full protocol including contrast-enhanced sequences.European radiology experimental · 2023Article
- Parametric maps of spatial two-tissue compartment model for prostate dynamic contrast enhanced MRI - comparison with the standard tofts model in the diagnosis of prostate cancer.Physical and engineering sciences in medicine · 2023Article
- Tumor localization by Prostate Imaging and Reporting and Data System (PI-RADS) version 2.1 predicts prognosis of prostate cancer after radical prostatectomy.Scientific reports · 2023Article
- Article
- Biparametric prostate MRI: impact of a deep learning-based software and of quantitative ADC values on the inter-reader agreement of experienced and inexperienced readers.La Radiologia medica · 2022Article
- Emerging MR methods for improved diagnosis of prostate cancer by multiparametric MRI.Magma (New York, N.Y.) · 2022Review
- Convolutional neural network-based reconstruction for acceleration of prostate TThe British journal of radiology · 2022Article
- Early experience in avoiding biopsies for biopsy-naïve men with clinical suspicion of prostate cancer but non-suspicious biparametric magnetic resonance imaging results and prostate-specific antigen density < 0.15 ng/mLActa radiologica open · 2022Article
Corrections and comments
- Erratum issuedCorrigendum.2017
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSince multiparametric magnetic resonance imaging (mp-MRI) of the prostate exceeds 30 min, minimizing the evaluation time of significant (Gleason scores > 6) prostate cancer (PCa) would be beneficial. A reduced protocol might be sufficient for the diagnosis. PURPOSE: To study whether a short unenhanced biparametric MRI (bp-MRI) matches mp-MRI in detecting significant PCa. MATERIAL AND
methodsA total of 204 men (median age, 65 years; mean ± SD, 64.1; range 45-75 years; median serum PSA level, 14 ng/mL; range, 2.2-120 ng/mL; median prostate volume, 60 mL; range, 23-263 mL) fulfilled the criteria for being enrolled. They underwent mp-MRI and prostate biopsy from January through June 2014. Of the included patients, 9.3% underwent prostatectomy, 90.7% had TRUS-bx, and 10.8 had MRI-targeted TRUS-bx. Two radiologists separately assessed the mp-MRI examination (T2-weighted [T2W] imaging, diffusion-weighted imaging [DWI], apparent diffusion coefficient map [ADC-map] and dynamic contrast-enhanced imaging [DCE]). Two months later, the bp-MRI version (T2W imaging, DWI, and ADC-map) was evaluated.
resultsReader 1: Assessing mp-MRI: 0 false negatives, sensitivity of 1, and specificity 0.04. Assessing bp-MRI: four false negatives, sensitivity of 0.94, and specificity 0.15. Reader 2: Assessing mp-MRI: five false negatives, sensitivity of 0.93, and specificity 0.16. Assessing bp-MRI: three false negatives, sensitivity of 0.96, and specificity 0.15. Intra-reader agreement Cohen's Kappa (κ) was 0.87 for reader 1 (95% confidence interval [CI], 0.83-0.92) and 0.84 for reader 2 (95% CI 0.78-0.89).
conclusionBp-MRI is as good as mp-MRI at detecting PCa. A large prospective study seems to be strongly warranted.
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