ReviewBiomaterials research2016
Solid organ fabrication: comparison of decellularization to 3D bioprinting.
Review in Biomaterials research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed.
- The making of cells and organs in xenogeneic animal bioreactor.Signal transduction and targeted therapy · 2026Review
- A simple, efficient technique to make colon crypt gels for 3D models.3D printing and additive manufacturing · 2025Article
- Embedded 3D bioprinting - An emerging strategy to fabricate biomimetic & large vascularized tissue constructs.Bioactive materials · 2024Review
- Raw Materials, Technology, Healthcare Applications, Patent Repository and Clinical Trials on 4D Printing Technology: An Updated Review.Pharmaceutics · 2022Review
- Bovine and human endometrium-derived hydrogels support organoid culture from healthy and cancerous tissues.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Application of 3D Bioprinting in Urology.Micromachines · 2022Review
- Decellularized Human Umbilical Tissue-Derived Hydrogels Promote Proliferation and Chondrogenic Differentiation of Mesenchymal Stem Cells.Bioengineering (Basel, Switzerland) · 2022Article
- Additive Manufacturing Strategies for Personalized Drug Delivery Systems and Medical Devices: Fused Filament Fabrication and Semi Solid Extrusion.Molecules (Basel, Switzerland) · 2022Review
- Engineering of thick human functional myocardium via static stretching and electrical stimulation.iScience · 2022Article
- Design by Nature: Emerging Applications of Native Liver Extracellular Matrix for Cholangiocyte Organoid-Based Regenerative Medicine.Bioengineering (Basel, Switzerland) · 2022Review
- Matrigel 3D bioprinting of contractile human skeletal muscle models recapitulating exercise and pharmacological responses.Communications biology · 2021Article
- Bioengineering of the Uterus.Reproductive sciences (Thousand Oaks, Calif.) · 2021Review
- A review of biomimetic scaffolds for bone regeneration: Toward a cell-free strategy.Bioengineering & translational medicine · 2021Review
- Utility of perfusion decellularization to achieve biochemical and mechanically accurate whole animal and organ-specific tissue scaffolds.Physiological reports · 2021Article
- Extrusion-Based Bioprinting of Multilayered Nanocellulose Constructs for Cell Cultivation UsingACS omega · 2021Article
- Bioprinting: From Tissue and Organ Development toChemical reviews · 2020Review
- Advanced Techniques for Skeletal Muscle Tissue Engineering and Regeneration.Bioengineering (Basel, Switzerland) · 2020Review
- Review
- Compensation of Disabled Organogeneses in Genetically Modified Pig Fetuses by Blastocyst Complementation.Stem cell reports · 2020Article
- Digital Design and Automated Fabrication of Bespoke Collagen Microfiber Scaffolds.Tissue engineering. Part C, Methods · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Solid organ fabrication is an ultimate goal of Regenerative Medicine. Since the introduction of Tissue Engineering in 1993, functional biomaterials, stem cells, tunable microenvironments, and high-resolution imaging technologies have significantly advanced efforts to regenerate in vitro culture or tissue platforms. Relatively simple flat or tubular organs are already in (pre)clinical trials and a few commercial products are in market. The road to more complex, high demand, solid organs including heart, kidney and lung will require substantive technical advancement. Here, we consider two emerging technologies for solid organ fabrication. One is decellularization of cadaveric organs followed by repopulation with terminally differentiated or progenitor cells. The other is 3D bioprinting to deposit cell-laden bio-inks to attain complex tissue architecture. We reviewed the development and evolution of the two technologies and evaluated relative strengths needed to produce solid organs, with special emphasis on the heart and other tissues of the cardiovascular system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.