ArticleThe Pan African medical journal2016
Characteristics and risk factors of preterm births in a tertiary center in Lagos, Nigeria.
Article in The Pan African medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Preterm birth and its associated factors in Ethiopia: a systematic review and meta-analysis.African health sciences · 2021Pooled it
- Adverse fetal outcomes and its associated factors in Ethiopia: a systematic review and meta-analysis.BMC pediatrics · 2020Pooled it
- Determinants of preterm birth among mothers who gave birth in East Africa: systematic review and meta-analysis.Italian journal of pediatrics · 2020Pooled it
- The effect of pregnancy induced hypertension and multiple pregnancies on preterm birth in Ethiopia: a systematic review and meta-analysis.BMC research notes · 2019Pooled it
- Intravenous versus oral iron for anaemia among pregnant women in Nigeria (IVON): an open-label, randomised controlled trial.The Lancet. Global health · 2024Trial
- Knowledge of mothers regarding prematurity and related problems in Abakaliki, South-East Nigeria.BMC pregnancy and childbirth · 2026Article
- Special care baby unit neonatal disease outcomes in a tertiary hospital in Nigeria: 2-year retrospective cross-sectional analysis.BMJ public health · 2025Article
- Association of Gestational Hypertension with Sociodemographic and Anthropometric Factors, Perinatal Outcomes, Breastfeeding Practices, and Mediterranean Diet Adherence: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2023Article
- Maternal, obstetric and gynecological factors associated with preterm birth in Rwanda: findings from a national longitudinal study.BMC pregnancy and childbirth · 2023Article
- A Scoping Review of Preterm Births in Sub-Saharan Africa: Burden, Risk Factors and Outcomes.International journal of environmental research and public health · 2022Article
- Prevalence of preterm birth and risk factors associated with it at different gestational ages: A multicenter retrospective survey in China.Saudi medical journal · 2022Article
- Clinical analysis on the influencing factors related to preterm twin pregnancy.Revista da Associacao Medica Brasileira (1992) · 2022Article
- Effects of HIV Infection on Pregnancy Outcomes Among Women Attending Antenatal Care in Referral Hospitals of the Amhara Regional State, Ethiopia: A Prospective Cohort Study.International journal of women's health · 2022Article
- Evaluation of the association between haemoglobin levels and preterm birth at Khartoum, Sudan: A hospital-based study.Frontiers in nutrition · 2022Article
- Prevalence of Sleep Problems and Its Association With Preterm Birth Among Kindergarten Children in a Rural Area of Shanghai, China.Frontiers in pediatrics · 2022Article
- Risk factors for preterm birth: a prospective cohort study.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
- Existing barriers to utilization of health services for maternal and newborn care in rural Western Kenya.BMC health services research · 2021Article
- Factors associated with preterm birth at Wachemo University Nigist Eleni Mohammed memorial hospital, southern Ethiopia: case-control study.BMC pregnancy and childbirth · 2021Article
- Determinants of Preterm Birth among Women Who Gave Birth in Amhara Region Referral Hospitals, Northern Ethiopia, 2018: Institutional Based Case Control Study.International journal of pediatrics · 2020Article
- Biological feasibility and importance of a gonorrhea vaccine for global public health.Vaccine · 2019Review
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Authors and funding
18 authors at 3 institutions in 2 countries.
Funding
Abstract
introductionPreterm birth is a dire complication of pregnancy that poses huge long-term medical and financial burdens for affected children, their families, and the health care system. The aim of the present study was to identify characteristics associated with preterm births at the Lagos University Teaching Hospital (LUTH), Lagos, Nigeria from 2011 to 2013.
methodsWe obtained Information from 5,561 maternal, fetal/neonatal and obstetric records from the labor ward. We excluded delivery at less than 22 weeks (0.25%), post-term birth at ≥42 weeks gestation (1.3%), and unknown gestation (1.4%). Additionally, we excluded records of multiple births (5.4%) and stillbirths (8.3%) leaving 4,691 records of singleton live-births for analysis. Logistic regression analysis was performed comparing preterm birth (22-36 weeks gestation) to term birth (37-41 weeks gestation). Multiple variable models adjusting for maternal age, parity, fetal position, delivery method and booking status were also evaluated. Multinomial regression was used to identify characteristics associated with preterm birth (PTB) defined as early PTB (22-31 weeks gestation), moderate PTB (32-34 weeks gestation), late PTB (35-36 weeks gestation), compared to term birth (37-41 completed weeks gestation).
resultsFrom our data, 16.8% of the singleton live-birth deliveries were preterm (<37 weeks gestation). Of these, 4.7% were early (22-31 weeks), 4.5% were moderate (32-34 weeks) and 7.7% were late (35-36) PTBs. Older maternal age (≥35 years) [odds ratio (OR) = 1.41], hypertension (OR = 3.44) and rupture of membranes (OR = 4.03) were significantly associated with increased odds of PTB. Women being treated for the prevention of mother-to-child transmission of HIV were at a significantly decreased risk for PTB (OR = 0.70). Sixteen percent of women in this cohort were not registered for antenatal care in LUTH. These non-registered subjects had significantly greater odds of all categories of PTB, including early (odds ratio (OR) = 20.8), moderate (OR = 8.68), and late (OR = 2.15).
conclusionPTB and risks for PTB remain high in Nigeria. We recommend that any high risk pregnancy should be referred to a tertiary center for prenatal care in order to significantly reduce adverse birth outcomes such as PTBs.
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