ArticleGut pathogens2016
Antimicrobial resistance and integron gene cassette arrays in commensal Escherichia coli from human and animal sources in IRI.
Article in Gut pathogens, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled prevalence of Escherichia coli phenotypic and genotypic antimicrobial resistance profiles in poultry: systematic review and meta-analysis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Pooled it
- Pathotype-specific antimicrobial resistance in diarrheagenicFrontiers in microbiology · 2026Review
- Antimicrobial multidrug resistance of Escherichia coli from broiler farms in Zhanjiang, China.PloS one · 2025Article
- Prevalence and Antimicrobial Susceptibility of Foodborne Pathogens from Raw Livestock Meat in China, 2021.Microorganisms · 2024Article
- Detecting Class 1 Integrons and Their Variable Regions inAntibiotics (Basel, Switzerland) · 2024Article
- Antimicrobial resistance in food-associatedBioscience of microbiota, food and health · 2024Review
- Distribution pattern of antibiotic resistance genes inVeterinary world · 2023Article
- Genomic Characteristics of a Multidrug-Resistant ST648Infection and drug resistance · 2023Article
- Integrons in the development of antimicrobial resistance: critical review and perspectives.Frontiers in microbiology · 2023Review
- Article
- First study on virulence genes, antimicrobial resistance, and integrons inVeterinary world · 2022Article
- Risk of sharing resistant bacteria and/or resistance elements between dogs and their owners.BMC veterinary research · 2022Article
- Antimicrobial resistance in the globalized food chain: a One Health perspective applied to the poultry industry.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Review
- Multidrug resistance, biofilm formation, and virulence genes ofVeterinary world · 2021Article
- Impact of spent engine oil contamination on the antibiotic resistome of a tropical agricultural soil.Ecotoxicology (London, England) · 2021Article
- High incidence of multidrug resistance and class 1 and 2 integrons inVeterinary research forum : an international quarterly journal · 2021Article
- Assessing the benefits of composting poultry manure in reducing antimicrobial residues, pathogenic bacteria, and antimicrobial resistance genes: a field-scale study.Environmental science and pollution research international · 2020Article
- Live Bacterial Prophylactics in Modern Poultry.Frontiers in veterinary science · 2020Review
- Prevalence of class 1 integron inTropical medicine and health · 2020Article
- Molecular and Phenotypic Characteristics ofBioMed research international · 2019Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe human and animal intestinal tract harbors a complex community of microbes which enables bacteria to inherit antibiotic resistance genes. The aims of this study were to investigate clonality, antimicrobial resistance, prevalence and gene cassette arrays of class I and II integrons among commensal Escherichia coli from human and animals.
methodsA total of 200 E. coli isolates from human, chicken, cattle, and sheep were isolated followed by phenotypic antibiotic susceptibility testing and detection of class I and II integrons gene cassettes arrays. The clonal relationship of the isolates were analyzed by (GTG)5-PCR.
resultsOf 200 isolates, 136 isolates were multi drug resistance (MDR) including 47, 40, 31 and 18 isolates from chicken, human, cattle and sheep, respectively. Class I integron was detected in 50, 38, 6 and 16 %, while class II was detected in 26, 8, 0 and 4 % of chicken, human, cattle and sheep isolates, respectively. Variable regions were amplified and sequenced. Cassette arrays in class I integrons were: dfrA1, dfrA5, dfrA7, dfrA12, aadA1, dfrA17 aadA1, aadA22, aadB-aadA2 and dfrA12-orfF-aadA2, and for class II, dfrA1-sat-aadA1, and sat-sat1-aadA1 were detected. Six class I and three class II positive strains did not produce any amplicons for variable region. Integron-positive isolates showed higher rate of resistance to streptomycin and trimethoprim-sulphamethoxazole, especially in chicken isolates which were fed antibiotics. Low similarity and great genetic diversity of class I and II integrons carrying isolates indicated no clonal relation.
conclusionsIntegrons encoding for antibiotic resistance are significantly present among non-pathogenic commensal E. coli, especially from the hosts medicated by antibiotics. Uncontrolled use of antibiotics will increase the numbers of multiple drug resistant isolates and integrons prevalence.
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