Evidence map›Paper›PMID 27582780›Full record

ArticleAnnals of general psychiatry2016

A prospective hospital study of alcohol use disorders, comorbid psychiatric conditions and withdrawal prognosis.

Philippe Nubukpo, Murielle Girard, Jean-Marie Sengelen, Sophie Bonnefond, Aurélien Varnoux, Benoît Marin, Dominique Malauzat

Open access · goldAbstract read
In one paragraph

Article in Annals of general psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Inflammatory Biomarkers, Microbiome, Depression, and Executive Dysfunction in Alcohol Users.International journal of environmental research and public health · 2020
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Philippe NubukpoPôle Addictologie, Centre Hospitalier Esquirol, 15 rue du Dr Marcland, 87025 Limoges, France ; Département de Recherche et Développement (DRD), Centre Hospitalier Esquirol, 87025 Limoges, France ; Faculté de Médecine, UMR/INSERM1094, 2 rue du Dr Marcland, 87025 Limoges, France.
Murielle GirardDépartement de Recherche et Développement (DRD), Centre Hospitalier Esquirol, 87025 Limoges, France.
Jean-Marie SengelenPôle de Psychiatrie Infanto Juvénile, Centre Hospitalier Esquirol, 87025 Limoges, France.
Sophie BonnefondPôle de Psychiatrie Adulte, Centre Hospitalier Esquirol, 87025 Limoges, France.
Aurélien VarnouxPôle de Psychiatrie Adulte, Centre Hospitalier Esquirol, 87025 Limoges, France.
Benoît MarinFaculté de Médecine, UMR/INSERM1094, 2 rue du Dr Marcland, 87025 Limoges, France.
Dominique MalauzatDépartement de Recherche et Développement (DRD), Centre Hospitalier Esquirol, 87025 Limoges, France.
Centre Hospitalier Esquirol de Limoges · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe objective of this study was to describe the profile and alcoholic status of a population with alcohol use disorders (AUD) requesting help from a psychiatric hospital to stop drinking, as well as their clinical outcome and care consumption over the 2 years following the request.

methodsThe visits were conducted at baseline (M0) and at 6, 12, 18 and 24 months (M6, M12, M18, M24). Demographic, clinical and psychometric data [Beck Depression Inventory (BDI), AUDIT questionnaire, Global Assessment of Functioning (GAF) scale], and information regarding the use of psychiatric care and therapeutics were collected.

resultsThe 330 subjects included were mostly male, aged 45.2 ± 10.2 years with an employment rate of 55.4 %, living alone (69.1 %), with a psychiatric comorbidity (60.9 %), especially depressive, and with few somatic complications. Their global functioning was poor (GAF score 49.14 ± 15.6), and less than 10 % were addicted to another substance. The abstinence rate at 24 months was 41.4 %, but only 23 % (20) abstained continuously between M0 and M24, and 66.7 % (58) intermittently. The likelihood of abstinence at M24 was greater for females aged over 60 years. The BDI score decreased significantly between M0 and M24. In all, 56.2 % of the participants were re-hospitalized after weaning, but were not integrated in long-term medical care.

conclusionsAbstinence after alcohol withdrawal fluctuated over time indicating the need for long-term support. The treatment of AUD should not target total, continuous abstinence. Prognostic profiles combining socio-demographic, clinical and biological indicators must be established.

Indexed as

AbstinenceAlcoholComorbidityPsychiatric carePsychiatryWithdrawal

Identifiers

PMID27582780
PMCPMC5006587
OpenAlexW2516045207

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.