ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017
Essential Role of DNA Methyltransferase 1-mediated Transcription of Insulin-like Growth Factor 2 in Resistance to Histone Deacetylase Inhibitors.
Expression of concernAbstract read
In one paragraph
Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 16 papers.
0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
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- Chromatin modifiers in human disease: from functional roles to regulatory mechanisms.Molecular biomedicine · 2024Review
- FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma.Cell death & disease · 2022Article
- The contributing factors of resistance or sensitivity to epigenetic drugs in the treatment of AML.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022Review
- Cigarette smoke-induced LKB1/AMPK pathway deficiency reduces EGFR TKI sensitivity in NSCLC.Oncogene · 2021Article
- Emerging Nano-Based Strategies Against Drug Resistance in Tumor Chemotherapy.Frontiers in bioengineering and biotechnology · 2021Review
- Expanding the Structural Diversity of DNA Methyltransferase Inhibitors.Pharmaceuticals (Basel, Switzerland) · 2020Article
- Small molecule-induced simultaneous destabilization of β-catenin and RAS is an effective molecular strategy to suppress stemness of colorectal cancer cells.Cell communication and signaling : CCS · 2020Article
- Long Non-Coding RNA: Dual Effects on Breast Cancer Metastasis and Clinical Applications.Cancers · 2019Review
- Epigenetic inhibition of the tumor suppressor ARHI by light at night-induced circadian melatonin disruption mediates STAT3-driven paclitaxel resistance in breast cancer.Journal of pineal research · 2019Article
- Molecular and Clinical Opposite Findings in 11p15.5 Associated Imprinting Disorders: Characterization of Basic Mechanisms to Improve Clinical Management.International journal of molecular sciences · 2019Review
- The enhancement of combination of berberine and metformin in inhibition of DNMT1 gene expression through interplay of SP1 and PDPK1.Journal of cellular and molecular medicine · 2018Article
- Do social insects support Haig's kin theory for the evolution of genomic imprinting?Epigenetics · 2017Review
- Targeting the PD-L1/DNMT1 axis in acquired resistance to sorafenib in human hepatocellular carcinoma.Oncology reports · 2017Article
- B1, a novel HDAC inhibitor, induces apoptosis through the regulation of STAT3 and NF-κB.International journal of molecular medicine · 2017Article
- H19 promotes endometrial cancer progression by modulating epithelial-mesenchymal transition.Oncology letters · 2017Article
Corrections and comments
- Expression of concern
Authors and funding
17 authors at 5 institutions in 4 countries.
Hye-Young Min *Creative Research Initiative Center for concurrent control of emphysema and lung cancer, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Su-Chan Lee *Creative Research Initiative Center for concurrent control of emphysema and lung cancer, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Jong Kyu Woo *Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Hyun Jin JungInterdisciplinary Program in Genetic Engineering, Seoul National University, Seoul 08826, Republic of Korea.
Kwan Hee ParkCreative Research Initiative Center for concurrent control of emphysema and lung cancer, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Hae Min JeongCollege of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Seung Yeob HyunCreative Research Initiative Center for concurrent control of emphysema and lung cancer, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Jaebeom ChoCreative Research Initiative Center for concurrent control of emphysema and lung cancer, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Wooin LeeCollege of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Ji Eun ParkCollege of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
So Jung KwonCollege of Pharmacy, Inje University, Gimhae, Gyungnam 50834, Republic of Korea.
Hyo-Jong LeeCollege of Pharmacy, Inje University, Gimhae, Gyungnam 50834, Republic of Korea.
Xiao NiDepartment of Dermatology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
Young Kee ShinCollege of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Faye M JohnsonDepartment of Thoracic Head & Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
Madeleine DuvicDepartment of Dermatology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
Ho-Young LeeCreative Research Initiative Center for concurrent control of emphysema and lung cancer, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Seoul National University · KRCreative Research · GBInje University · KRThe University of Texas MD Anderson Cancer Center · USSeoul National University of Science and Technology · KR
Funding
Novel Strategy for Lung Cancer Treatment using IGFBP-3R01CA100816 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LEE, HO-YOUNG · 2004 to 2013
$2.0MNCI NIH HHS R01 CA100816
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsCCCTC-Binding FactorDNA (Cytosine-5-)-Methyltransferase 1DNA MethylationDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticHematologic NeoplasmsHistone Deacetylase InhibitorsHistone DeacetylasesHumansHydroxamic AcidsInsulin-Like Growth Factor IILung NeoplasmsMiceRNA, Long NoncodingSTAT3 Transcription FactorCCCTC-Binding FactorCTCF protein, humanDNA (Cytosine-5-)-Methyltransferase 1DNMT1 protein, humanH19 long non-coding RNAHistone Deacetylase InhibitorsHistone DeacetylasesHydroxamic AcidsIGF2 protein, humanInsulin-Like Growth Factor IIRNA, Long NoncodingSTAT3 protein, humanSTAT3 Transcription FactorVorinostat
Identifiers
What OpenQuestion holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.