ReviewNature reviews. Disease primers2016
Infective endocarditis.
Review in Nature reviews. Disease primers, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06266741 (The Predictive Value of Lubricin in Patients With Infective Endocarditis), which is not on this map. Cited by 236 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Predictive Value of Lubricin in Patients With Infective Endocarditis
Who cites it
236 citing papers in PubMed, 2 syntheses or guidelines pooled it, 386 citations in OpenAlex.
- Recent infective endocarditis research findings suggest dentists prescribe prophylactic antibiotics for patients having a bicuspid aortic valve or mitral valve prolapse.Medicina oral, patologia oral y cirugia bucal · 2023Pooled it
- Time to abandon ampicillin plus gentamicin in favour of ampicillin plus ceftriaxone in Enterococcus faecalis infective endocarditis? A meta-analysis of comparative trials.Clinical research in cardiology : official journal of the German Cardiac Society · 2022Pooled it
- Article
- Tricuspid Valve Infective Endocarditis Seen on Point-of-Care Ultrasound: A Case Report.Cureus · 2026Article
- Cardiac immunity and heart repair: Mechanism, challenge, and future direction.Chinese medical journal · 2026Review
- Host interactomes ofMicrobiology spectrum · 2026Article
- Clinical and Epidemiological Landscape of Antimicrobial Resistance and Virulence inAntibiotics (Basel, Switzerland) · 2026Review
- Article
- A genome-wide in vivo screen reveals fitness pathways required for streptococcal infective endocarditis.PLoS pathogens · 2026Article
- Fatal Prosthetic Valve Endocarditis After Transcatheter Tricuspid Valve Replacement: Specialist Cardiac Autopsy Findings.JACC. Case reports · 2026Article
- Changing Patterns in Infective Endocarditis: A Contemporary Epidemiological Perspective.Pathogens (Basel, Switzerland) · 2026Review
- Percutaneous pharmacomechanical thrombectomy using AngioJet® for acute limb ischaemia due to infective endocarditis: a case report.European heart journal. Case reports · 2026Article
- Enterococcus faecalis-associated infective aortic endocarditis as a cause of arterial thromboembolism in a cat.Veterinary research communications · 2026Article
- A genome-widebioRxiv : the preprint server for biology · 2026Article
- Septic coronary embolism presenting as anterior STEMI: a stentless PCI strategy guided by clinical inconsistency and pathological confirmation-case report.European heart journal. Case reports · 2026Article
- Current Management of Infective Endocarditis: A Narrative Review Focused on Unmet Clinical Needs and the Multidisciplinary Approach.Journal of cardiovascular development and disease · 2026Review
- Review
- A case of chronic Campylobacter fetus infection-related glomerulonephritis, mimicking systemic autoimmune diseases.CEN case reports · 2026Article
- Gut-Heart Axis and Infective Endocarditis: How Microbiota Dysbiosis Shapes Cardiovascular Risk and Infection Susceptibility.Journal of clinical medicine · 2026Review
- Atypical mitral valve infective endocarditis presenting with fever and left upper abdominal pain due to splenic infarction: a case report.Frontiers in medicine · 2026Article
176 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
Infective endocarditis (IE) is a rare, life-threatening disease that has long-lasting effects even among patients who survive and are cured. IE disproportionately affects those with underlying structural heart disease and is increasingly associated with health care contact, particularly in patients who have intravascular prosthetic material. In the setting of bacteraemia with a pathogenic organism, an infected vegetation may form as the end result of complex interactions between invading microorganisms and the host immune system. Once established, IE can involve almost any organ system in the body. The diagnosis of IE may be difficult to establish and a strategy that combines clinical, microbiological and echocardiography results has been codified in the modified Duke criteria. In cases of blood culture-negative IE, the diagnosis may be especially challenging, and novel microbiological and imaging techniques have been developed to establish its presence. Once diagnosed, IE is best managed by a multidisciplinary team with expertise in infectious diseases, cardiology and cardiac surgery. Antibiotic prophylaxis for the prevention of IE remains controversial. Efforts to develop a vaccine that targets common bacterial causes of IE are ongoing, but have not yet yielded a commercially available product.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.