ArticleAllergy, asthma & immunology research2016
The Basophil Activation Test Is Safe and Useful for Confirming Drug-Induced Anaphylaxis.
Article in Allergy, asthma & immunology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- Drug-induced anaphylaxis: Molecular pathophysiology, diagnosis, and management.Asia Pacific allergy · 2026Article
- Eperisone-induced immediate hypersensitivity reactions.The Korean journal of internal medicine · 2026Review
- Drug hypersensitivity to vancomycin confirmed by basophil activation test: case report.The Pan African medical journal · 2025Article
- Clavulanic Acid Is a Leading Culprit Beta-Lactam in Immediate Allergic Reactions to Penicillins.Allergy, asthma & immunology research · 2023Article
- Cardiopulmonary arrest caused by nafamostat mesylate during hemodialysis.Clinical case reports · 2022Article
- Case of a 6-year-old boy with anaphylaxis induced by erythritol with positive skin prick test and negative basophil activation test.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2022Article
- Clinical characteristics and allergen detection of perioperative anaphylaxis: a 12-year retrospective analysis from an anesthesia clinic in China.Perioperative medicine (London, England) · 2022Article
- Testing Strategies and Predictors for Evaluating Immediate and Delayed Reactions to Cephalosporins.The journal of allergy and clinical immunology. In practice · 2021Article
- A Case Report of a 3-Year-Old Child With Anaphylactic Shock After a Diclofenac Suppository Confirmed by Serial Tryptase and a Basophil Activation Test.Frontiers in pediatrics · 2021Article
- A Case of Anaphylaxis in Which a Basophil Activation Test Was Used to Identify the Suspected Agent.Anesthesia progress · 2020Article
- Vascular endothelial growth factor-activated basophils in asthmatics.Postepy dermatologii i alergologii · 2020Article
- Refractory Unforeseen Anaphylaxis Case in a Rural OR Unit.Case reports in surgery · 2020Article
- Efficacy and Safety of Sublingual Immunotherapy in Elderly Rhinitis Patients Sensitized to House Dust Mites.Allergy, asthma & immunology research · 2018Article
- An Ofloxacin-Induced Anaphylaxis through an IgG4-Mediated but Not IgE-Mediated Basophil Activation Mechanism.Korean journal of critical care medicine · 2017Article
- The pathophysiology of anaphylaxis.The Journal of allergy and clinical immunology · 2017Review
- Drug-induced anaphylaxis in the emergency room.Acute medicine & surgery · 2017Review
- Usefulness of In Vivo and In Vitro Diagnostic Tests in the Diagnosis of Hypersensitivity Reactions to Quinolones and in the Evaluation of Cross-Reactivity: A Comprehensive Study Including the Latest Quinolone Gemifloxacin.Allergy, asthma & immunology research · 2017Article
- Levodropropizine-Induced Anaphylaxis: Case Series and Literature Review.Allergy, asthma & immunology research · 2017Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The basophil activation test (BAT) has been suggested as a complementary method for diagnosing drug allergies. The aim of this study was to evaluate the clinical utility of this test in patients with drug-induced anaphylaxis. In total, 19 patients, all of whom had a history of moderate to severe anaphylaxis, were enrolled. None of the causative drugs had available in vitro tests or reliable skin tests; these drugs included, among others, first and second-generation cephalosporins, H2 blockers, and muscle relaxants. The BAT yielded positive results in 57.9% of the cases, which was similar those results of skin prick and intradermal tests (42.1% and 57.9%, respectively). When basophils were double labelled with CD63 and CD203c, both of which are basophil activation markers, the positive rate was increased from 57.9% to 73.7%. Therefore, the results of this study confirm that the BAT is a quick, reliable, and safe diagnostic tool for patients with drug-induced anaphylaxis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.