ArticleScientific reports2016
Genomic and transcriptomic analyses of the tangerine pathotype of Alternaria alternata in response to oxidative stress.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 59 citations in OpenAlex.
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- Functional Characterization of Deubiquitinase UBP Family and Proteomic Analysis of Aaubp14-Mediated Pathogenicity Mechanism inJournal of fungi (Basel, Switzerland) · 2025Article
- Development of an RPA-CRISPR/Cas12a-Based Rapid Diagnosis Strip for the Tangerine Pathotype ofMicroorganisms · 2025Article
- A Cytochrome P450 AaCP1 Is Required for Conidiation and Pathogenicity in the Tangerine Pathotype ofMicroorganisms · 2025Article
- TheMicrobiology spectrum · 2023Article
- 3,4‑Dihydroxyacetophenone attenuates oxidative stress‑induced damage to HUVECs via regulation of the Nrf2/HO‑1 pathway.Molecular medicine reports · 2022Article
- Histone Methylation Is Required for Virulence, Conidiation, and Multi-Stress Resistance ofFrontiers in microbiology · 2022Article
- Genome-Wide Identification and Functional Characterization of GATA Transcription Factor Gene Family inJournal of fungi (Basel, Switzerland) · 2021Article
- Comparison of Four Systems to Test the Tolerance of 'Fortune' Mandarin Tissue Cultured Plants toPlants (Basel, Switzerland) · 2021Article
- The critical role ofApplied and environmental microbiology · 2021Article
- Histone Acetyltransferases and Deacetylases Are Required for Virulence, Conidiation, DNA Damage Repair, and Multiple Stresses Resistance ofFrontiers in microbiology · 2021Article
- Accessory Chromosome-Acquired Secondary Metabolism in Plant Pathogenic Fungi: The Evolution of Biotrophs Into Host-Specific Pathogens.Frontiers in microbiology · 2021Review
- Phylogenomics of Plant-AssociatedFrontiers in microbiology · 2021Article
- Transcriptomic Insights into the Antifungal Effects of Magnolol on the Growth and Mycotoxin Production ofToxins · 2020Article
- The basal transcription factor II H subunit Tfb5 is required for stress response and pathogenicity in the tangerine pathotype of Alternaria alternata.Molecular plant pathology · 2020Article
- Overview ofIndian journal of microbiology · 2020Review
- Article
- A Small Horizontally Transferred Gene Cluster Contributes to the Sporulation of Alternaria alternata.Genome biology and evolution · 2019Article
- Genomic features and evolution of the conditionally dispensable chromosome in the tangerine pathotype of Alternaria alternata.Molecular plant pathology · 2019Article
- Oxidative Stress Response ofMicroorganisms · 2019Article
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Authors and funding
6 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The tangerine pathotype of Alternaria alternata produces the A. citri toxin (ACT) and is the causal agent of citrus brown spot that results in significant yield losses worldwide. Both the production of ACT and the ability to detoxify reactive oxygen species (ROS) are required for A. alternata pathogenicity in citrus. In this study, we report the 34.41 Mb genome sequence of strain Z7 of the tangerine pathotype of A. alternata. The host selective ACT gene cluster in strain Z7 was identified, which included 25 genes with 19 of them not reported previously. Of these, 10 genes were present only in the tangerine pathotype, representing the most likely candidate genes for this pathotype specialization. A transcriptome analysis of the global effects of H2O2 on gene expression revealed 1108 up-regulated and 498 down-regulated genes. Expressions of those genes encoding catalase, peroxiredoxin, thioredoxin and glutathione were highly induced. Genes encoding several protein families including kinases, transcription factors, transporters, cytochrome P450, ubiquitin and heat shock proteins were found associated with adaptation to oxidative stress. Our data not only revealed the molecular basis of ACT biosynthesis but also provided new insights into the potential pathways that the phytopathogen A. alternata copes with oxidative stress.
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