ArticleNature2016
Alzheimer's disease: Attack on amyloid-β protein.
Article in Nature, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pharmacological and Clinical Heterogeneity of Anti-Amyloid Monoclonal Antibodies in Early Alzheimer's Disease: A Systematic Review and Meta-Analysis of Randomized Trials.Medical sciences (Basel, Switzerland) · 2026Pooled it
- Liraglutide improves cognition function in streptozotocin-induced diabetic rats by downregulating β-secretase and γ-secretase and alleviating oxidative stress in HT-22 cells.Endocrine journal · 2025Article
- A one-two punch targeting reactive oxygen species and fibril for rescuing Alzheimer's disease.Nature communications · 2024Article
- Therapeutic Strategies Aimed at Improving Neuroplasticity in Alzheimer Disease.Pharmaceutics · 2023Review
- Article
- Design, synthesis and evaluation of quinolinone derivatives containing dithiocarbamate moiety as multifunctional AChE inhibitors for the treatment of Alzheimer's disease.Journal of enzyme inhibition and medicinal chemistry · 2020Article
- Pharmacotherapy of Alzheimer's Disease: Seeking Clarity in a Time of Uncertainty.Frontiers in pharmacology · 2020Review
- Defragmentation of lysozyme derived Amyloid β fibril using Biocompatible Magnetic fluid.Journal of materials science. Materials in medicine · 2018Article
- Converging pathways in neurodegeneration, from genetics to mechanisms.Nature neuroscience · 2018Review
- TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease.The Journal of experimental medicine · 2018Article
- Opening the debate on deep brain stimulation for Alzheimer disease - a critical evaluation of rationale, shortcomings, and ethical justification.BMC medical ethics · 2018Article
- Blocking beta 2-adrenergic receptor inhibits dendrite ramification in a mouse model of Alzheimer's disease.Neural regeneration research · 2017Article
- Parsing disease-relevant protein modifications from epiphenomena: perspective on the structural basis of SOD1-mediated ALS.Journal of mass spectrometry : JMS · 2017Article
- UB-311, a novel UBIThAlzheimer's & dementia (New York, N. Y.) · 2017Article
- D-4F decreases the expression of Aβ protein through up-regulating long non coding RNA sirt1-as in SAMP8 mice.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2017Article
- Hyperbaric Oxygen Prevents Cognitive Impairments in Mice Induced by D-Galactose by Improving Cholinergic and Anti-apoptotic Functions.Neurochemical research · 2017Article
- Alzheimer disease in 2016: Putting AD treatments and biomarkers to the test.Nature reviews. Neurology · 2017Review
- Retinoid X receptor ligand regulates RXRα/Nur77-dependent apoptosis via modulating its nuclear export and mitochondrial targeting.International journal of clinical and experimental pathology · 2017Article
- APP as a Protective Factor in Acute Neuronal Insults.Frontiers in molecular neuroscience · 2017Review
- Is Beta-Amyloid Accumulation a Cause or Consequence of Alzheimer's Disease?Journal of Alzheimer's parkinsonism & dementia · 2016Article
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
27582214What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.