ArticleScientific reports2016
ANGIOGENES: knowledge database for protein-coding and noncoding RNA genes in endothelial cells.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 29 citations in OpenAlex.
- Complications and comorbidities associated with antineoplastic chemotherapy: Rethinking drug design and delivery for anticancer therapy.Acta pharmaceutica Sinica. B · 2024Review
- An endothelial regulatory module links blood pressure regulation with elite athletic performance.PLoS genetics · 2024Article
- Genetic architecture of cardiac dynamic flow volumes.Nature genetics · 2024Article
- LncRNA ARGI Contributes to Virus-Induced Pancreatic β Cell Inflammation Through Transcriptional Activation of IFN-Stimulated Genes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Magnetique: an interactive web application to explore transcriptome signatures of heart failure.Journal of translational medicine · 2022Article
- FibroDB: Expression Analysis of Protein-Coding and Long Non-Coding RNA Genes in Fibrosis.Non-coding RNA · 2022Article
- Long Non Coding RNA Based Regulation of Cerebrovascular Endothelium.Frontiers in genetics · 2022Review
- Article
- Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses.Scientific reports · 2021Article
- Uncharacterized RNAs in Plasma of Alzheimer's Patients Are Associated with Cognitive Impairment and Show a Potential Diagnostic Power.International journal of molecular sciences · 2020Article
- Pan-tissue transcriptome analysis of long noncoding RNAs in the American beaver Castor canadensis.BMC genomics · 2020Article
- The Regulatory Roles of Non-coding RNAs in Angiogenesis and Neovascularization From an Epigenetic Perspective.Frontiers in oncology · 2019Review
- Identification of Cancer-Related Long Non-Coding RNAs Using XGBoost With High Accuracy.Frontiers in genetics · 2019Article
- Short and Long Noncoding RNAs Regulate the Epigenetic Status of Cells.Antioxidants & redox signaling · 2018Review
- Computational analysis of ribonomics datasets identifies long non-coding RNA targets of γ-herpesviral miRNAs.Nucleic acids research · 2018Article
- Long Non-coding RNAs in Endothelial Biology.Frontiers in physiology · 2018Review
- Article
- The Function and Therapeutic Potential of Long Non-coding RNAs in Cardiovascular Development and Disease.Molecular therapy. Nucleic acids · 2017Review
- microRNA dependent and independent deregulation of long non-coding RNAs by an oncogenic herpesvirus.PLoS pathogens · 2017Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing evidence indicates the presence of long noncoding RNAs (lncRNAs) is specific to various cell types. Although lncRNAs are speculated to be more numerous than protein-coding genes, the annotations of lncRNAs remain primitive due to the lack of well-structured schemes for their identification and description. Here, we introduce a new knowledge database "ANGIOGENES" (http://angiogenes.uni-frankfurt.de) to allow for in silico screening of protein-coding genes and lncRNAs expressed in various types of endothelial cells, which are present in all tissues. Using the latest annotations of protein-coding genes and lncRNAs, publicly-available RNA-seq data was analyzed to identify transcripts that are expressed in endothelial cells of human, mouse and zebrafish. The analyzed data were incorporated into ANGIOGENES to provide a one-stop-shop for transcriptomics data to facilitate further biological validation. ANGIOGENES is an intuitive and easy-to-use database to allow in silico screening of expressed, enriched and/or specific endothelial transcripts under various conditions. We anticipate that ANGIOGENES serves as a starting point for functional studies to elucidate the roles of protein-coding genes and lncRNAs in angiogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.