SynthesisPharmacoEconomics2016
Nocturia Work Productivity and Activity Impairment Compared with Other Common Chronic Diseases.
Synthesis in PharmacoEconomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Sacubitril/valsartan improves nocturia in hypertensive patients: a pilot study.Translational andrology and urology · 2026Article
- Insomnia Proven to be Associated With Prostate Cancer: A Genetic Correlation Study Incorporating Lifestyle Factors.Alpha psychiatry · 2025Article
- The mediating effect of sleep quality in the relationship between nocturia and psychosocial functions in nurses: a cross-sectional survey based on TARGET.BMC nursing · 2025Article
- Association of domain-specific physical activity with nocturia: a population-based study.Scientific reports · 2025Article
- Impact of urinary catheters including reusable catheters on quality of life and work productivity in persons with spinal cord lesion.Scientific reports · 2024Article
- Psychometric properties and moderated mediation analysis of the ICIQ-NQOL in Chinese primary care patients with nocturia.Journal of patient-reported outcomes · 2024Article
- Course and predictors of work productivity in gout - results from the NOR-Gout longitudinal 2-year treat-to-target study.Rheumatology (Oxford, England) · 2023Article
- The effect of treatment on work productivity in patients with bladder cancer.Urologic oncology · 2023Article
- Partially different? The importance of general equilibrium in health economic evaluations: An application to nocturia.Health economics · 2023Article
- Direct healthcare resource utilisation, health-related quality of life, and work productivity in patients with moderate rheumatoid arthritis: an observational study.BMC musculoskeletal disorders · 2021Observational
- Construct validity of the Post-COVID-19 Functional Status Scale in adult subjects with COVID-19.Health and quality of life outcomes · 2021Article
- Health-Related Quality of Life and Productivity Among US Patients with Severe Asthma.Journal of asthma and allergy · 2021Article
- The socioeconomic burden of chronic lung disease in low-resource settings across the globe - an observational FRESH AIR study.Respiratory research · 2019Observational
- Economic Burden of Illness in Adult Patients with Nocturia.Journal of managed care & specialty pharmacy · 2019Article
- Patients' Lived Experiences of Nocturia: A Qualitative Study of the Evening, the Night, and the Next Day.The patient · 2017Article
- A practical approach to the management of nocturia.International journal of clinical practice · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe International Continence Society defines nocturia as the need to void one or more times during the night, with each of the voids preceded and followed by sleep. The chronic sleep disturbance and sleep deprivation experienced by patients with nocturia affects quality of life, compromising both mental and physical well-being. This paper aims to characterise the burden of nocturia by comparing published data from patients with nocturia with data from patients with any of 12 other common chronic conditions, specifically focusing on its impact on work productivity and activity impairment, as measured by the instrument of the same name (WPAI).
methodsA systematic literature review of multiple data sources identified evaluable studies for inclusion in the analysis. Study eligibility criteria included use of the WPAI instrument in patients with one of a predefined list of chronic conditions. We assessed the quality of each included study using the Newcastle-Ottawa scale and extracted basic study information, work and activity impairment data. To assess how work and activity impairment from nocturia compares with impairment from other common chronic diseases, we conducted two data syntheses (pooled and unpooled).
resultsThe number of evaluable studies and the range of overall work productivity impairment reported, respectively, were as follows: nocturia (3; 14-39 %), overactive bladder (5; 11-41 %), irritable bowel syndrome/constipation (14; 21-51 %), gastroesophageal reflux disease (GERD) (13; 6-42 %), asthma/allergies (11; 6-40 %), chronic obstructive pulmonary disease (COPD) (7; 19-42 %), sleep problems (3; 12-37 %), arthritis (13; 21-69 %), pain (9; 29-64 %), depression (4; 15-43 %) and gout (2; 20-37 %).
conclusionsThe overall work productivity impairment as a result of nocturia is substantial and was found to be similar to impairment observed as a result of several other more frequently researched common chronic diseases. Greater awareness of the burden of nocturia, a highly bothersome and prevalent condition, will help policy makers and healthcare decision makers provide appropriate management of nocturia.
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