Trial reportBMC public health2016
Effectiveness of a smartphone app on improving immunization of children in rural Sichuan Province, China: a cluster randomized controlled trial.
Trial report in BMC public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care.The Cochrane database of systematic reviews · 2025Pooled it
- Impact of measles vaccination strategies on vaccination rates in low-income and middle-income countries: a systematic review and meta-analysis.BMJ global health · 2025Pooled it
- Exploring characteristics and common features of digital health in pediatric care in developing countries: a systematic review.Frontiers in digital health · 2025Pooled it
- Effectiveness of Catch-Up Vaccination Interventions Versus Standard or Usual Care Procedures in Increasing Adherence to Recommended Vaccinations Among Different Age Groups: Systematic Review and Meta-Analysis of Randomized Controlled Trials and Before-After Studies.JMIR public health and surveillance · 2024Pooled it
- The effect of mHealth on childhood vaccination in Africa: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Interventions for improving coverage of childhood immunisation in low- and middle-income countries.The Cochrane database of systematic reviews · 2023Pooled it
- Short message service (SMS) reminders for childhood immunisation in low-income and middle-income countries: a systematic review and meta-analysis.BMJ global health · 2021Pooled it
- Community health worker-based mobile health (mHealth) approaches for improving management and caregiver knowledge of common childhood infections: A systematic review.Journal of global health · 2020Pooled it
- Use of Apps to Promote Childhood Vaccination: Systematic Review.JMIR mHealth and uHealth · 2020Pooled it
- Patient reminder and recall interventions to improve immunization rates.The Cochrane database of systematic reviews · 2018Pooled it
- Design of an Automated Mobile Phone-Based Reminder and Incentive System: Application in a Quasi-Randomized Controlled Trial to Improve the Timeliness of Childhood Vaccinations in Tanzania.JMIR formative research · 2025Trial
- Impact of mobile phone delivered reminders and unconditional incentives on measles-containing vaccine timeliness and coverage: a randomised controlled trial in western Kenya.BMJ global health · 2021Trial
- Modernizing Vaccination Data System: Design, Development, and Deployment of a Digital Vaccination Registry in Liberia, 2023-2025.Vaccines · 2026Article
- Strategies and challenges for immunisation of children under 5 years in primary health care in different countries: a scoping review.BMC public health · 2025Article
- Strengthening Immunization Data: Protocol for the Evaluation of an Electronic Immunization Register.JMIR research protocols · 2025Article
- Mobile health interventions on vaccination coverage among children under 5 years of age in Low and Middle-Income countries; a scoping review.Frontiers in public health · 2025Article
- Outcomes and Costs of the Transition From a Paper-Based Immunization System to a Digital Immunization System in Vietnam: Mixed Methods Study.Journal of medical Internet research · 2024Article
- Leveraging Community Health Workers and a Responsive Digital Health System to Improve Vaccination Coverage and Timeliness in Resource-Limited Settings: Protocol for a Cluster Randomized Type 1 Effectiveness-Implementation Hybrid Study.JMIR research protocols · 2024Article
- Article
- Interventions addressing routine childhood immunization and its behavioral and social drivers.Frontiers in public health · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to assess the effectiveness of an EPI smartphone application (EPI app) on improving vaccination coverage in rural Sichuan Province, China.
methodsThis matched-pair cluster randomized controlled study included 32 village doctors, matched in 16 pairs, and took place from 2013 to 2015. Village doctors in the intervention group used the EPI app and reminder text messages while village doctors in the control group used their usual procedures and text messages. The primary outcome was full vaccination coverage with all five vaccines (1 dose of BCG, 3 doses of hepatitis B, 3 doses of OPV, 3 doses of DPT and 1 dose of measles vaccine), and the secondary outcome was coverage with each dose of the five individual vaccines. We also conducted qualitative interviews with village doctors to understand perceptions on using the EPI app and how this changed their vaccination work.
resultsThe full vaccination coverage increased statistically significant from baseline to end-line in both the intervention (67 % [95 % CI:58-75 %] to 84 % [95 % CI:76-90 %], P = 0.028) and control group (71 % [95 % CI:62-79 %] to 82 % [95 % CI:74-88 %], P = 0.014). The intervention group had higher increase in full vaccination coverage from baseline to end-line compared to the control group (17 % vs 10 %), but this was not statistically significant (P = 0.164). Village doctors found it more convenient to use the EPI app to manage child vaccination and also reported saving time by looking up information of caregivers and contacting caregivers for overdue vaccinations quicker. However, village doctors found it hard to manage children who migrated out of the counties.
conclusionsThis study showed that an app and text messages can be used by village doctors to improve full vaccination coverage, though no significant increase in vaccination coverage was found when assessing the effect of the app on its own. Village doctors using EPI app reported having improved their working efficiency of managing childhood vaccination. Future studies should be conducted to evaluate the impact of more integrated approach of mHealth intervention on child immunization.
trial registrationChinese Clinical Trials Registry (ChiCTR): ChiCTR-TRC- 13003960 , registered on December 6, 2013.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.