ReviewInflammopharmacology2016
Probiotic bacteria: a viable adjuvant therapy for relieving symptoms of rheumatoid arthritis.
Review in Inflammopharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Effects of Microecological Regulators on Rheumatoid Arthritis: A Systematic Review and Meta-Analysis of Randomized, Controlled Trials.Nutrients · 2023Pooled it
- Efficacy of Probiotics in Rheumatoid Arthritis and Spondyloarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Nutrients · 2022Pooled it
- The efficacy of probiotic supplementation in rheumatoid arthritis: a meta-analysis of randomized, controlled trials.Inflammopharmacology · 2018Pooled it
- The therapeutic effect of probiotics on rheumatoid arthritis: a systematic review and meta-analysis of randomized control trials.Clinical rheumatology · 2017Pooled it
- Immunomodulatory properties of the gut microbiome: diagnostic and therapeutic potential for rheumatoid arthritis.Clinical and experimental medicine · 2025Review
- Role of Gut Microbiota in the Development and Management of Rheumatoid Arthritis: A Narrative Review.Cureus · 2023Review
- Enhanced Anti-Inflammatory Effect of the Combination ofMolecules (Basel, Switzerland) · 2022Article
- Modification of bacterial cells forFrontiers in bioengineering and biotechnology · 2022Article
- Intestinal microbiome-rheumatoid arthritis crosstalk: The therapeutic role of probiotics.Frontiers in microbiology · 2022Review
- Targeting Probiotics in Rheumatoid Arthritis.Nutrients · 2021Review
- Probiotic Supplementation for Rheumatoid Arthritis: A Promising Adjuvant Therapy in the Gut Microbiome Era.Frontiers in pharmacology · 2021Review
- Comment on "Dysregulation of gut microbiome is linked to disease activity of rheumatic diseases".Clinical rheumatology · 2020Article
- Efficacy of synbiotic supplementation in improving rheumatoid arthritis.Research in pharmaceutical sciences · 2020Article
- Intraarticular Injection of Infliximab-Loaded Thermosensitive Hydrogel Alleviates Pain and Protects Cartilage in Rheumatoid Arthritis.Journal of pain research · 2020Article
- Mini-Review: Human Microbiome and Rheumatic Diseases.Frontiers in cellular and infection microbiology · 2020Review
- Role of Diet in Influencing Rheumatoid Arthritis Disease Activity.The open rheumatology journal · 2018Review
- Don't neglect nutrition in rheumatoid arthritis!RMD open · 2018Article
- The Role of High-Mobility Group Box-1 and Its Crosstalk with Microbiome in Rheumatoid Arthritis.Mediators of inflammation · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The burgeoning use of probiotics has proliferated during the past two decades. However, the effect of probiotic administration for either the prevention or treatment of rheumatoid arthritis (RA) has been investigated in a limited number of studies. Randomized controlled clinical trials have provided evidences that specific probiotics supplementation exhibit anti-inflammatory effects, help to increase daily activities and alleviate symptoms in patients with RA. Therefore, using probiotic bacteria as an adjuvant therapy may be considered as a promising treatment option for RA. This review summarizes the available data about the therapeutic and preventive effect of probiotics in RA, together with probiotic supplement as a possible therapy in clinical treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.