Evidence map›Paper›PMID 27581561›Full record

ArticleAnimal science journal = Nihon chikusan Gakkaiho2016

Synbiotics suppress the release of lactate dehydrogenase, promote non-specific immunity and integrity of jejunum mucosa in piglets.

Zuzana Andrejčáková, Drahomíra Sopková, Radoslava Vlčková, Lucia Kulichová, Soňa Gancarčíková, Viera Almášiová, Katarína Holovská, Vladimír Petrilla, Lenka Krešáková

Open access · bronzeAbstract read
In one paragraph

Article in Animal science journal = Nihon chikusan Gakkaiho, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zuzana AndrejčákováDepartment of Anatomy, Histology and Physiology, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovak Republic.
Drahomíra SopkováDepartment of Anatomy, Histology and Physiology, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovak Republic.
Radoslava VlčkováDepartment of Anatomy, Histology and Physiology, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovak Republic.
Lucia KulichováDepartment of Epizootology and Preventive Veterinary Medicine, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovak Republic.
Soňa GancarčíkováDepartment of Microbiology and Immunology, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovak Republic.
Viera AlmášiováDepartment of Anatomy, Histology and Physiology, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovak Republic.
Katarína HolovskáDepartment of Anatomy, Histology and Physiology, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovak Republic.
Vladimír PetrillaDepartment of Anatomy, Histology and Physiology, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovak Republic.
Lenka KrešákováDepartment of Anatomy, Histology and Physiology, University of Veterinary Medicine and Pharmacy in Košice, Košice, Slovak Republic.
University of Veterinary Medicine in Košice · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of our experiment was to study how synbiotics are able to deal with the problems of post-weaning piglets. Lactobacillus plantarum - Biocenol(TM) LP96 (CCM 7512), Lactobacillus fermentum - Biocenol(TM) LF99 (CCM 7514) and flaxseed (rich in n-3 polyunsaturated fatty acids) were administered to 36 conventional piglets from a problematic breed with confirmed presence of enterotoxigenic Escherichia coli and Coronavirus. The experimental piglets were supplied with probiotic cheeses and crushed flax-seed in the period starting 10 days before weaning and lasting up to 14 days post-weaning. Piglets in the control group were supplied only control cheese. The impact of such additives on the release of lactate dehydrogenase (LDH; spectroscopic and electrophoretic assay), alteration of immunity (index of metabolic activity), jejunum histology (light microscopy), and health of conventional piglets from a problematic breed (monitoring of hematology, consistency and moisture of feces and body temperature) were examined. We found significant decrease in LDH leakage in the blood serum and tissue extracts, indicating better cell membrane integrity in the individual organs of animals. Probiotics and flaxseed applied together seem to be a good source of nutrients to improve the immune status and the integrity of jejunum mucosa during infection. © 2015 Japanese Society of Animal Science.

Indexed as

Animal FeedFlaxImmunity, InnateLactiplantibacillus plantarumLimosilactobacillus fermentumAnimal Nutritional Physiological PhenomenaAnimalsCell MembraneCoronavirusEscherichia coliIntestinal MucosaJejunumL-Lactate DehydrogenaseMicroscopy, Electron, TransmissionSwineSynbioticsL-Lactate Dehydrogenasegut histologylactate dehydrogenasenon-specific immunitypigletsynbiotics

Identifiers

PMID27581561
PMCPMC7159591
OpenAlexW2282235346

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.