Evidence map›Paper›PMID 27581536›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2017

Association of worsening arterial stiffness with incident heart failure in asymptomatic patients with cardiovascular risk factors.

Hiroe Aisu, Makoto Saito, Shinji Inaba, Toru Morofuji, Kayo Takahashi, Takumi Sumimoto, Takafumi Okura, Jitsuo Higaki

Abstract read
PubMed Publisher
In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Adenosine AJournal of the American Heart Association · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Deletion of the microRNA-degrading nuclease, translin/trax, prevents pathogenic vascular stiffness.American journal of physiology. Heart and circulatory physiology · 2019
    Article
  11. Determinants of pulse pressure amplification in hypertensive and diabetic patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2019
    Article
  12. Article
  13. Review
  14. Healthy aging and carotid performance: strain measures and β-stiffness index.Hypertension research : official journal of the Japanese Society of Hypertension · 2018
    Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hiroe AisuDepartment of Cardiology, Kitaishikai Hospital, Ozu, Japan.
Makoto SaitoDepartment of Cardiology, Kitaishikai Hospital, Ozu, Japan.
Shinji InabaDepartment of Cardiology, Kitaishikai Hospital, Ozu, Japan.
Toru MorofujiDepartment of Cardiology, Kitaishikai Hospital, Ozu, Japan.
Kayo TakahashiDepartment of Cardiology, Kitaishikai Hospital, Ozu, Japan.
Takumi SumimotoDepartment of Cardiology, Kitaishikai Hospital, Ozu, Japan.
Takafumi OkuraDepartment of Cardiology, Pulmonology, Hypertension and Nephrology, Ehime University Graduate School of Medicine, Toon, Japan.
Jitsuo HigakiDepartment of Cardiology, Pulmonology, Hypertension and Nephrology, Ehime University Graduate School of Medicine, Toon, Japan.
Ehime University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the independent and incremental role of worsening arterial stiffness in new-onset heart failure (HF) in patients with preclinical HF. We retrospectively studied 456 consecutive asymptomatic patients with HF risk factors (hypertension, obesity, type 2 diabetes mellitus, atrial fibrillation and ischemic heart disease) who underwent paired applanation tonometry examinations (median interval of 2.4 years) during 2006-2011. Brachial ankle pulse wave velocity (baPWV) was measured as a surrogate marker of arterial stiffness. Patients were followed up for admission for new-onset HF over a median duration of 4.9 years after the second examination. HF was observed in 30 patients (7%). The change in baPWV (∆baPWV) was significantly associated with hospitalization for new-onset HF, independent of and incremental to comorbidities, renal dysfunction, left ventricular (LV) dysfunction and baPWV at baseline. Even in patients with an LV ejection fraction of ⩾40%, ∆baPWV was significantly associated with hospitalization for new-onset HF after similar adjustments. When the patients were divided into groups based on this cutoff value of ⩾15% ∆baPWV and the generally accepted external cutoff value of ⩾1750 cm s

Indexed as

AdultAgedAged, 80 and overAnkle Brachial IndexCardiovascular DiseasesEchocardiographyFemaleHeart FailureHumansIncidenceMaleMiddle AgedPulse Wave AnalysisRetrospective StudiesRisk FactorsVascular Stiffness

Identifiers

PMID27581536
OpenAlexW2510820137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.