Evidence map›Paper›PMID 27581480›Full record

ArticleJournal of the Royal Society, Interface2016

Inferring R0 in emerging epidemics-the effect of common population structure is small.

Pieter Trapman, Frank Ball, Jean-Stéphane Dhersin, Viet Chi Tran, Jacco Wallinga, Tom Britton

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  3. Article
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  5. Epidemic models: why and how to use them.Anaesthesia, critical care & pain medicine · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Range of reproduction number estimates for COVID-19 spread.Biochemical and biophysical research communications · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Inferring generation-interval distributions from contact-tracing data.Journal of the Royal Society, Interface · 2020
    Article
  16. Article
  17. Estimation in emerging epidemics: biases and remedies.Journal of the Royal Society, Interface · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pieter TrapmanDepartment of Mathematics, Stockholm University, Stockholm, Sweden ptrapman@math.su.se.ORCID 0000-0003-0569-1659
Frank BallSchool of Mathematical Sciences, University of Nottingham, Nottingham, UK.
Jean-Stéphane DhersinLAGA, CNRS (UMR 7539), Université Paris 13, Sorbonne Paris Cité, France.
Viet Chi TranLaboratoire Paul Painlevé, Université des Sciences et Technologies de Lille, Villeneuve-d'Ascq, France.
Jacco WallingaRijksinstituut voor Volksgezondheid en Milieu (RIVM), Bilthoven, The Netherlands Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands.
Tom BrittonDepartment of Mathematics, Stockholm University, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When controlling an emerging outbreak of an infectious disease, it is essential to know the key epidemiological parameters, such as the basic reproduction number R0 and the control effort required to prevent a large outbreak. These parameters are estimated from the observed incidence of new cases and information about the infectious contact structures of the population in which the disease spreads. However, the relevant infectious contact structures for new, emerging infections are often unknown or hard to obtain. Here, we show that, for many common true underlying heterogeneous contact structures, the simplification to neglect such structures and instead assume that all contacts are made homogeneously in the whole population results in conservative estimates for R0 and the required control effort. This means that robust control policies can be planned during the early stages of an outbreak, using such conservative estimates of the required control effort.

Indexed as

Disease OutbreaksModels, BiologicalPopulation DynamicsHumansInfectionsemerging epidemicsinfectious disease modellingpopulation structureR0real-time spread

Identifiers

PMID27581480
PMCPMC5014060

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.