Evidence map›Paper›PMID 27581467›Full record

ArticleReproductive health2016

Incidence of intrapartum stillbirth and associated risk factors in tertiary care setting of Nepal: a case-control study.

Ashish Kc, Johan Wrammert, Uwe Ewald, Robert B Clark, Jageshwor Gautam, Gehanath Baral, Kedar P Baral, Mats Målqvist

Open access · goldAbstract readComparative Study
In one paragraph

Article in Reproductive health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

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  13. Impact of Action Taken in Response to Stillbirth Audit: A Success Story.Journal of obstetrics and gynaecology of India · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Ashish KcInternational Maternal and Child Health, Department of Women's and Children's Health, University Hospital, SE-751 85, Uppsala, Sweden. aaashis7@yahoo.com.ORCID http://orcid.org/0000-0002-0541-4486
Johan WrammertInternational Maternal and Child Health, Department of Women's and Children's Health, University Hospital, SE-751 85, Uppsala, Sweden.
Uwe EwaldInternational Maternal and Child Health, Department of Women's and Children's Health, University Hospital, SE-751 85, Uppsala, Sweden.
Robert B ClarkLatter-day Saint Charities, Salt Lake City, UT, USA.
Jageshwor GautamParopakar Maternity and Women's Hospital, Thapathali, Nepal.
Gehanath BaralParopakar Maternity and Women's Hospital, Thapathali, Nepal.
Kedar P BaralPatan Academy of Health Sciences, Lalitpur, Nepal.
Mats MålqvistInternational Maternal and Child Health, Department of Women's and Children's Health, University Hospital, SE-751 85, Uppsala, Sweden.
Uppsala University Hospital · SECatholic Charities · USPatan Academy of Health Sciences · NPUnited Nations Children's Fund · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEach year, 1.2 million intrapartum stillbirths occur globally. In Nepal, about 50 % of the total number of stillbirths occur during the intrapartum period. An understanding of the risk factors associated with intrapartum stillbirth will facilitate the development of preventative strategies to reduce the associated burden of death. This study was conducted in a tertiary-care setting with the aim to identify risk factors associated with intrapartum stillbirth.

methodsA case-control study was completed from July 2012 to September 2013. All women who had an intrapartum stillbirth during the study period were included as cases, and 20 % of women with live births were randomly selected upon admission to create the referent population. Relevant information was retrieved from clinical records for case and referent women. In addition, interviews were completed with each woman to determine their demographic and obstetric history.

resultsDuring the study period, 4,476 women were enrolled as referents and 136 women had intrapartum stillbirths. The following factors were found to be associated with an increased risk for intrapartum stillbirth: poor familial wealth quintile (Adj OR 1.8, 95 % CI-1.1-3.4); less maternal education (Adj OR, 3.2 95 % CI-1.8-5.5); lack of antenatal care (Adj OR, 4.8 95 % CI 3.2-7.2); antepartum hemorrhage (Adj OR 2.1, 95 % CI 1.1-4.2); multiple births (Adj. OR-3.0, 95 % CI- 1.9-5.4); obstetric complication during labor (Adj. OR 4.5, 95 % CI-2.9-6.9); lack of fetal heart rate monitoring per protocol (Adj. OR-1.9, 95 % CI 1.5-2.4); lack of partogram use (Adj. OR-2.1, 95 % CI 1.1-4.1); small-for-gestational age (Adj. OR-1.8, 95 % CI-1.2-1.7); preterm birth (Adj. OR-5.4, 95 % CI 3.5-8.2); and being born preterm with a small-for-gestational age (Adj. OR-9.0, 95 % CI 7.3-15.5).

conclusionBeing born preterm with a small-for-gestational age was associated with the highest risk for intrapartum stillbirth. Inadequate fetal heart rate monitoring and partogram use are preventable risk factors associated with intrapartum stillbirth; by increasing adherence to these interventions the risk of intrapartum stillbirth can be reduced. The association of the lack of appropriate antenatal care with intrapartum stillbirth indicates that quality antenatal care may improve fetal health and outcomes.

trial registrationISRCTN97846009.

Indexed as

Obstetric Labor ComplicationsPregnancy ComplicationsAdultCase-Control StudiesFemaleGestational AgeHumansIncidenceInfant, NewbornMaternal AgeNepalPregnancyProspective StudiesRisk FactorsStillbirthTertiary Health Care

Identifiers

PMID27581467
PMCPMC5007702
OpenAlexW2199569624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.