ReviewJournal of industrial microbiology & biotechnology2016
Yeast factories for the production of aromatic compounds: from building blocks to plant secondary metabolites.
Review in Journal of industrial microbiology & biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed.
- Engineering yeast for sustainable bioproduction of tryptophan-derived aromatic compounds.FEMS yeast research · 2026Review
- A Review of the Progress in the Microbial Biosynthesis of Prenylated Aromatic Compounds.Molecules (Basel, Switzerland) · 2025Review
- The Application of Multiple Strategies to Enhance Methylparaben Synthesis Using the EngineeredBiology · 2025Article
- Engineering the L-tryptophan metabolism for efficient de novo biosynthesis of tryptophol in Saccharomyces cerevisiae.Biotechnology for biofuels and bioproducts · 2024Article
- Metabolic and tolerance engineering of Komagataella phaffii for 2-phenylethanol production through genome-wide scanning.Biotechnology for biofuels and bioproducts · 2024Article
- Aromatic secondary metabolite production from glycerol was enhanced by amino acid addition in Pichia pastoris.Applied microbiology and biotechnology · 2023Article
- Xylose and shikimate transporters facilitates microbial consortium as a chassis for benzylisoquinoline alkaloid production.Nature communications · 2023Article
- Flavonoid Production: Current Trends in Plant Metabolic Engineering and De Novo Microbial Production.Metabolites · 2023Review
- Biotechnological production of specialty aromatic and aromatic-derivative compounds.World journal of microbiology & biotechnology · 2022Review
- From Biomass-DerivedFrontiers in chemistry · 2022Review
- Resveratrol production from several types of saccharide sources by a recombinantMetabolic engineering communications · 2021Article
- Transcriptomic analysis of synchrony and productivity in self-cycling fermentation of engineered yeast producing shikimic acid.Biotechnology reports (Amsterdam, Netherlands) · 2021Article
- Yarrowia lipolytica chassis strains engineered to produce aromatic amino acids via the shikimate pathway.Microbial biotechnology · 2021Article
- Multi-modular engineering of Saccharomyces cerevisiae for high-titre production of tyrosol and salidroside.Microbial biotechnology · 2021Article
- Integrating continuous hypermutation with high-throughput screening for optimization of cis,cis-muconic acid production in yeast.Microbial biotechnology · 2021Article
- Crystal structures of non-oxidative decarboxylases reveal a new mechanism of action with a catalytic dyad and structural twists.Scientific reports · 2021Article
- Enhanced Protocatechuic Acid Production From Glucose UsingFrontiers in bioengineering and biotechnology · 2021Article
- Harnessing the Endogenous 2μ Plasmid ofFrontiers in microbiology · 2021Article
- Fermentative production of Vitamin E tocotrienols in Saccharomyces cerevisiae under cold-shock-triggered temperature control.Nature communications · 2020Article
- EngineeringSynthetic and systems biotechnology · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aromatic amino acid biosynthesis pathway is a source to a plethora of commercially relevant chemicals with very diverse industrial applications. Tremendous efforts in microbial engineering have led to the production of compounds ranging from small aromatic molecular building blocks all the way to intricate plant secondary metabolites. Particularly, the yeast Saccharomyces cerevisiae has been a great model organism given its superior capability to heterologously express long metabolic pathways, especially the ones containing cytochrome P450 enzymes. This review contains a collection of state-of-the-art metabolic engineering work devoted towards unraveling the mechanisms for enhancing the flux of carbon into the aromatic pathway. Some of the molecules discussed include the polymer precursor muconic acid, as well as important nutraceuticals (flavonoids and stilbenoids), and opium-derived drugs (benzylisoquinoline alkaloids).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.