Evidence map›Paper›PMID 27581358›Full record

ArticleBlood2016

Normal hematologic parameters and fetal hemoglobin silencing with heterozygous IKZF1 mutations.

Nour Abdulhay, Claudia Fiorini, Attila Kumánovics, Ashleigh A Sun, Jeannette Hansen-Rejali, Karl V Voelkerding, Sergio D Rosenzweig, Harry R Hill, Vijay G Sankaran

Abstract readCase ReportsLetter
In one paragraph

Article in Blood, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nour AbdulhayDivision of Hematology/Oncology, Boston Children's Hospital, Boston, MA.
Claudia FioriniDivision of Hematology/Oncology, Boston Children's Hospital, Boston, MA.
Attila KumánovicsARUP Institute for Clinical and Experimental Pathology, ARUP Laboratories, Salt Lake City, UT.
Ashleigh A SunImmunology Service, Department of Laboratory Medicine, Clinical Center, and Primary Immune Deficiency Clinic, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD; and.
Jeannette Hansen-RejaliARUP Institute for Clinical and Experimental Pathology, ARUP Laboratories, Salt Lake City, UT.
Karl V VoelkerdingARUP Institute for Clinical and Experimental Pathology, ARUP Laboratories, Salt Lake City, UT.
Sergio D RosenzweigDepartment of Pathology, University of Utah, Salt Lake City, UT.
Harry R HillARUP Institute for Clinical and Experimental Pathology, ARUP Laboratories, Salt Lake City, UT.
Vijay G SankaranDivision of Hematology/Oncology, Boston Children's Hospital, Boston, MA.

Funding

Translational and clinical studies targeting y-globin modulationU01HL117720 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI SANKARAN, VIJAY GANESH · 2013 to 2017
$7.4M
Systematic Genetic Dissection of Human ErythropoiesisR01DK103794 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI Vijay Ganesh Sankaran · 2014 to 2026
$5.9M
Identifying Genome-wide Association Study-Nominated Regulators of ErythropoiesisR33HL120791 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI SANKARAN, VIJAY GANESH · 2016 to 2018
$1.7M
Expanding the Genetic Basis of Common Variable ImmunodeficiencyR03AI113631 · NIAID · UNIVERSITY OF UTAH · PI KUMANOVICS, ATTILA · 2014 to 2015
$149k
Mutation Analysis Of Selected Lymphoid Immune DisordersZIACL010304 · CLC · CLINICAL CENTER · PI ROSENZWEIG, SERGIO · 2009 to 2025
$0k
NHLBI NIH HHS R33 HL120791NHLBI NIH HHS U01 HL117720NIAID NIH HHS R03 AI113631NIDDK NIH HHS R01 DK103794
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HeterozygoteMutation, MissenseAdultChildChild, PreschoolCommon Variable ImmunodeficiencyFamilyFemaleFetal HemoglobinGene SilencingHumansIkaros Transcription FactorMalePedigreeFetal HemoglobinIkaros Transcription FactorIKZF1 protein, human

Identifiers

PMID27581358
PMCPMC5073187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.