Evidence map›Paper›PMID 27580146›Full record

ArticleMedicine and science in sports and exercise2017

Objectively Measured Physical Activity and Cognitive Function in Older Adults.

Wenfei Zhu, Virginia G Wadley, Virginia J Howard, Brent Hutto, Steven N Blair, Steven P Hooker

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicine and science in sports and exercise, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it.

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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenfei Zhu1School of Physical Education, Shaanxi Normal University, Xi'an, Shaanxi, CHINA; 2Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL; 3Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL; 4Prevention Research Center, Arnold School of Public Health, University of South Carolina, Columbia, SC; 5Departments of Exercise Science and Epidemiology/Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC; and 6Exercise Science and Health Promotion Program, College of Health Solutions, Arizona State University, Phoenix, AZ.
Virginia G Wadley
Virginia J Howard
Brent Hutto
Steven N Blair
Steven P Hooker

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
Impact of Physical Activity on Stroke and Cognitive Function in Older AdultsR01NS061846 · NINDS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI HOOKER, STEVEN PAUL · 2008 to 2012
$2.9M
NINDS NIH HHS R01 NS061846NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

purposeEmerging evidence suggests physical activity (PA) is associated with cognitive function. To overcome limitations of self-report PA measures, this study investigated the association of accelerometer-measured PA with incident cognitive impairment and longitudinal cognition among older adults.

methodsParticipants were recruited from the cohort study Reasons for Geographic and Racial Differences in Stroke in the United States. Accelerometers provided PA measures, including the percentage of total accelerometer wearing time spent in moderate-to-vigorous-intensity PA (MVPA%), light-intensity PA, and sedentary time for four to seven consecutive days at baseline. Cognitive impairment was defined by the Six-Item Screener. Letter fluency, animal fluency, word list learning, and Montreal Cognitive Assessment (orientation and recall) were conducted to assess executive function and memory.

resultsParticipants (N = 6452, 69.7 ± 8.5 yr, 55.3% women, 30.5% Black) with usable accelerometer and cognition measures spent extremely limited time in MVPA (1.5% ± 1.9% of accelerometer wearing time). During an average of 3 yr of follow-up, 346 cases of incident cognitive impairment were observed. After adjustments, participants in higher MVPA% quartiles had a lower risk of cognitive impairment (i.e., quartile 2: odds ratio = 0.64, 95% confidence interval = 0.48-0.84) and better maintenance in executive function (≥0.03 z-score units) and memory (≥0.12 z-score units) compared with quartile 1 (P < 0.05). Stratified analyses showed the same association among White adults, but higher MVPA% was associated with better maintenance of only memory among Black adults. No significance was found for light-intensity PA or sedentary time.

conclusionThere was a dose-response relationship between MVPA% and cognitive function in older adults, with higher levels associated with a 36% or lower risk of cognitive impairment and better maintenance of memory and executive function over time, particularly in White adults.

Indexed as

AccelerometryAgedBlack or African AmericanBlack PeopleCognitionCognition DisordersExecutive FunctionExerciseFemaleHumansIncidenceLongitudinal StudiesMaleMemoryUnited StatesWhite People

Identifiers

PMID27580146
PMCPMC5161659

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.