Evidence map›Paper›PMID 27579993›Full record

ArticleHearing research2016

The effects of aging and sex on detection of ultrasonic vocalizations by adult CBA/CaJ mice (Mus musculus).

Anastasiya Kobrina, Micheal L Dent

Abstract read
In one paragraph

Article in Hearing research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Blast trauma affects production and perception of mouse ultrasonic vocalizations.The Journal of the Acoustical Society of America · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Sex-based Differences in Hearing Loss: Perspectives From Non-clinical Research to Clinical Outcomess.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2020
    Review
  11. GABAJournal of neurophysiology · 2020
    Article
  12. Article
  13. A broad filter between call frequency and peripheral auditory sensitivity in northern grasshopper mice (Onychomys leucogaster).Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2019
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anastasiya KobrinaDepartment of Psychology, University at Buffalo-SUNY, Buffalo, NY 14260, USA. Electronic address: akobrina@buffalo.edu.
Micheal L DentDepartment of Psychology, University at Buffalo-SUNY, Buffalo, NY 14260, USA. Electronic address: mdent@buffalo.edu.

Funding

Complex Sound Perception in MiceR01DC012302 · NIDCD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI DENT, MICHEAL L · 2013 to 2017
$1.9M
NIDCD NIH HHS R01 DC012302
6 · The paper itself

Abstract

Mice are frequently used as animal models for human hearing research, yet their auditory capabilities have not been fully explored. Previous studies have established auditory threshold sensitivities for pure tone stimuli in CBA/CaJ mice using ABR and behavioral methodologies. Little is known about how they perceive their own ultrasonic vocalizations (USVs), and nothing is known about how aging influences this perception. The aim of the present study was to establish auditory threshold sensitivity for several USV types, as well as to track these thresholds across the mouse's lifespan. In order to determine how well mice detect these complex communication stimuli, several CBA/CaJ mice were trained and tested at various ages on a detection task using operant conditioning procedures. Results showed that mice were able to detect USVs into old age. Not surprisingly, thresholds differed for the different USV types. Male mice suffered greater hearing loss than females for all calls but not for 42 kHz tones. In conclusion, the results highlight the importance of studying complex signals across the lifespan.

Indexed as

Age FactorsAuditory ThresholdSex FactorsUltrasonicsVocalization, AnimalAcoustic StimulationAnimalsAuditory PerceptionFemaleMaleMiceMice, Inbred CBAPresbycusisRegression AnalysisSignal Processing, Computer-AssistedSoundAgingCBA/CaJ miceOperant conditioningPsychoacousticsUltrasonic vocalizationsUSVs

Identifiers

PMID27579993
PMCPMC5086433

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.