Evidence map›Paper›PMID 27579915›Full record

ArticleMedical care2017

Impact of a Value-based Formulary on Medication Utilization, Health Services Utilization, and Expenditures.

Kai Yeung, Anirban Basu, Ryan N Hansen, John B Watkins, Sean D Sullivan

Abstract read
In one paragraph

Article in Medical care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. How to make value-based health insurance designs more effective? A systematic review and meta-analysis.The European journal of health economics : HEPAC : health economics in prevention and care · 2019
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Drug use and spending under a formulary informed by cost-effectiveness.Journal of managed care & specialty pharmacy · 2023
    Article
  6. Cost-Effectiveness of Systemic Treatments for Metastatic Castration-Sensitive Prostate Cancer: An Economic Evaluation Based on Network Meta-Analysis.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2022
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Evolution of the AMCP Format for Formulary Submissions.Journal of managed care & specialty pharmacy · 2020
    Article
  12. Article
  13. Review
  14. Article
  15. Should national pharmacare apply a value-based insurance design?CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2019
    Article
  16. Are the Benefits of Value-Based Insurance Design Conclusive?Journal of managed care & specialty pharmacy · 2019
    Article
  17. Value-Based Insurance Design: Current Evidence and Future Directions.Journal of managed care & specialty pharmacy · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kai Yeung*Pharmaceutical Outcomes Research and Policy Program, University of Washington †Department of Health Services, School of Public Health, University of Washington, Seattle ‡Premera Blue Cross, Mountlake Terrace, WA.
Anirban Basu
Ryan N Hansen
John B Watkins
Sean D Sullivan

Funding

NRSA Training CoreTL1TR002318 · NCATS · UNIVERSITY OF WASHINGTON · PI Megan Moore · 2017 to 2026
$8.4M
Institute of Translational Health SciencesTL1TR000422 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$2.1M
Incentivizing Value in Managed Care Plans: Impact of a Value-Based FormularyR36HS023346 · AHRQ · UNIVERSITY OF WASHINGTON · PI YEUNG, KAI · 2014 to 2014
$40k
AHRQ HHS R36 HS023346NCATS NIH HHS TL1 TR000422NCATS NIH HHS TL1 TR002318
6 · The paper itself

Abstract

backgroundValue-based benefit design has been suggested as an effective approach to managing the high cost of pharmaceuticals in health insurance markets. Premera Blue Cross, a large regional health plan, implemented a value-based formulary (VBF) for pharmaceuticals in 2010 that explicitly used cost-effectiveness analysis (CEA) to inform medication copayments. OBJECTIVE OF THE STUDY: The objective of the study was to determine the impact of the VBF.

designInterrupted time series of employer-sponsored plans from 2006 to 2013. SUBJECTS: Intervention group: 5235 beneficiaries exposed to the VBF. CONTROL GROUP: 11,171 beneficiaries in plans without any changes in pharmacy benefits.

interventionThe VBF-assigned medications with lower value (estimated by CEA) to higher copayment tiers and assigned medications with higher value to lower copayment tiers. MEASURES: Primary outcome was medication expenditures from member, health plan, and member plus health plan perspectives. Secondary outcomes were medication utilization, emergency department visits, hospitalizations, office visits, and nonmedication expenditures.

resultsIn the intervention group after VBF implementation, member medication expenditures increased by $2 per member per month (PMPM) [95% confidence interval (CI), $1-$3] or 9%, whereas health plan medication expenditures decreased by $10 PMPM (CI, $18-$2) or 16%, resulting in a net decrease of $8 PMPM (CI, $15-$2) or 10%, which translates to a net savings of $1.1 million. Utilization of medications moved into lower copayment tiers increased by 1.95 days' supply (CI, 1.29-2.62) or 17%. Total medication utilization, health services utilization, and nonmedication expenditures did not change.

conclusionsCost-sharing informed by CEA reduced overall medication expenditures without negatively impacting medication utilization, health services utilization, or nonmedication expenditures.

Indexed as

Formularies as TopicAdolescentAdultChildChild, PreschoolCost SharingDrug UtilizationFees, PharmaceuticalFinancing, PersonalHealth ExpendituresHealth ServicesHumansInfantInfant, NewbornInsurance, Pharmaceutical ServicesMiddle AgedPrescription Drugs

Identifiers

PMID27579915
PMCPMC5233590

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.