Evidence map›Paper›PMID 27579717›Full record

ArticleMagnetic resonance in medicine2017

Self-gated MRI of multiple beat morphologies in the presence of arrhythmias.

Francisco Contijoch, Srikant Kamesh Iyer, James J Pilla, Paul Yushkevich, Joseph H Gorman, Robert C Gorman, Harold Litt, Yuchi Han, Walter R T Witschey

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Francisco ContijochSchool of Medicine, University of California - San Diego, San Diego, California, USA.ORCID 0000-0001-9616-3274
Srikant Kamesh IyerDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
James J PillaDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Paul YushkevichDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Joseph H GormanDepartment of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Robert C GormanDepartment of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Harold LittDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Yuchi HanDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Walter R T WitscheyDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
University of Pennsylvania · USUniversity of California San Diego · US

Funding

Surgery to Prevent Post Infarction Ventricular RemodelingR01HL063954 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI GORMAN, ROBERT C · 2001 to 2018
$9.8M
Adaptive Large-Scale Framework for Automatic Biomedical Image SegmentationR01EB017255 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI YUSHKEVICH, PAUL A. · 2014 to 2018
$3.0M
Nuclear Magnetic Tirho Relaxation in Acute and Chronic Myocardial InfarctionsR00HL108157 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WITSCHEY, WALTER R.T. · 2014 to 2016
$747k
Use of Real Time MRI for Evaluation of Regional Myocardial FunctionF31HL120580 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CONTIJOCH, FRANCISCO J · 2014 to 2015
$49k
NHLBI NIH HHS F31 HL120580NHLBI NIH HHS R00 HL108157NHLBI NIH HHS R01 HL063954NIBIB NIH HHS R01 EB017255
6 · The paper itself

Abstract

purposeDevelop self-gated MRI for distinct heartbeat morphologies in subjects with arrhythmias.

methodsGolden angle radial data was obtained in seven sinus and eight arrhythmias subjects. An image-based cardiac navigator was derived from single-shot images, distinct beat types were identified, and images were reconstructed for repeated morphologies. Image sharpness, contrast, and volume variation were quantified and compared with self-gated MRI. Images were scored for image quality and artifacts. Hemodynamic parameters were computed for each distinct beat morphology in bigeminy and trigeminy subjects and for sinus beats in patients with infrequent premature ventricular contractions.

resultsImages of distinct beat types were reconstructed except for two patients with infrequent premature ventricular contractions. Image contrast and sharpness were similar to sinus self-gated images (contrast = 0.45 ± 0.13 and 0.43 ± 0.15; sharpness = 0.21 ± 0.11 and 0.20 ± 0.05). Visual scoring was highest in self-gated images (4.1 ± 0.3) compared with real-time (3.9 ± 0.4) and ECG-gated cine (3.4 ± 1.5). ECG-gated cine had less artifacts than self-gating (2.3 ± 0.7 and 2.1 ± 0.2), but was affected by misgating in two subjects. Among arrhythmia subjects, post-extrasystole/sinus (58.1 ± 8.6 mL) and interrupted sinus (61.4 ± 5.9 mL) stroke volume was higher than extrasystole (32.0 ± 16.5 mL; P < 0.02).

conclusionSelf-gated imaging can reconstruct images during ectopy and allowed for quantification of hemodynamic function of different beat morphologies. Magn Reson Med 78:678-688, 2017. © 2016 International Society for Magnetic Resonance in Medicine.

Indexed as

AdultAgedAlgorithmsArrhythmias, CardiacHemodynamicsHumansImage Processing, Computer-AssistedMagnetic Resonance Imaging, CineMaleMiddle Agedarrhythmiascardiovascular magnetic resonancegolden anglenavigatorsnon-Cartesiannonperiodic motionradialreal timeretrospective cinesensitivity encoding

Identifiers

PMID27579717
PMCPMC5332534
OpenAlexW2518590517

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.