Evidence map›Paper›PMID 27579339›Full record

ArticleData in brief2016

Dataset of liver proteins of eu- and hypothyroid rats affected in abundance by any of three factors: in vivo exposure to hexabromocyclododecane (HBCD), thyroid status, gender differences.

I Miller, J Renaut, S Cambier, A J Murk, A C Gutleb, T Serchi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

I MillerInstitute for Medical Biochemistry, Department for Biomedical Sciences, University of Veterinary Medicine Vienna, Veterinaerplatz 1, A-1210 Vienna, Austria.
J RenautEnvironmental Research and Innovation (ERIN) Department, Luxembourg Institute of Science and Technology (LIST), 5, Avenue des Hauts-Fourneaux, L-4362 Esch-sur-Alzette, Luxembourg.
S CambierEnvironmental Research and Innovation (ERIN) Department, Luxembourg Institute of Science and Technology (LIST), 5, Avenue des Hauts-Fourneaux, L-4362 Esch-sur-Alzette, Luxembourg.
A J MurkWageningen University, Marine Animal Ecology Group, De Elst 1, 6708 WD Wageningen, The Netherlands.
A C GutlebEnvironmental Research and Innovation (ERIN) Department, Luxembourg Institute of Science and Technology (LIST), 5, Avenue des Hauts-Fourneaux, L-4362 Esch-sur-Alzette, Luxembourg.
T SerchiEnvironmental Research and Innovation (ERIN) Department, Luxembourg Institute of Science and Technology (LIST), 5, Avenue des Hauts-Fourneaux, L-4362 Esch-sur-Alzette, Luxembourg.
Luxembourg Institute of Science and Technology · LUUniversity of Veterinary Medicine Vienna · ATWageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Male Wistar rats with different thyroid status (eu-, hypothyroid) were exposed to 0, 3 or 30 mg/kg body weight of the flame retardant HBCD for 7 days and obtained data compared with a previous study in females, "Hexabromocyclododecane (HBCD) induced changes in the liver proteome of eu- and hypothyroid female rats" (Miller et al., 2016) [1]. Specifically, proteomic investigation of liver protein patterns obtained by 2D-DIGE was performed and differences between animals groups recorded, based on the factors exposure, thyroid status and gender. All proteins with significantly changed abundance in any of these comparisons were identified by mass spectrometry. General, hormone and proteomic data of both the present and the previous studies are discussed in Miller et al. (2016) [1] and in "Gender specific differences in the liver proteome of rats exposed to hexabromocyclododecane (HBCD)" Miller et al. (2016) [2].

Indexed as

A1AT_RAT, Alpha-1-antiproteinaseACOX1_RAT, Peroxisomal acyl-coenzyme A oxidase 1AGT2_RAT, Alanine–glyoxylate aminotransferase 2_mitochondrialAK1D1_RAT, 3-oxo-5-beta-steroid 4-dehydrogenaseAL1B1_RAT, Aldehyde dehydrogenase X_mitochondrialBHMT1_RAT, Betaine–homocysteine S-methyltransferase 1CAH3_RAT, Carbonic anhydrase 3DOPD_RAT, D-dopachrome decarboxylaseFABPL_RAT, Fatty acid-binding protein_liverFRIL1_RAT, Ferritin light chain 1Gender-specific effectsGRP78_RAT, 78 kDa glucose-regulated proteinGSTA1_RAT, Glutathione S-transferase alpha-1GSTA2_RAT, Glutathione S-transferase alpha-2GSTA3_RAT, Glutathione S-transferase alpha-3GSTP1_RAT, Glutathione S-transferase PHBA_RAT, Hemoglobin subunit alpha-1/2HBCDHPT_RAT, HaptoglobinHypothyroidismK2C8_RAT, Keratin_type II cytoskeletal 8KNT2_RAT, T-kininogen 2LiverM2GD_RAT, Dimethylglycine dehydrogenase_mitochondrialPON1_RAT, Serum paraoxonase/arylesterase 1PON3_RAT, Serum paraoxonase/lactonase 3PRDX3_RAT, Thioredoxin-dependent peroxide reductase_mitochondrialProteomicsRatRD23B_RAT, UV excision repair protein RAD23 homolog BRET1_RAT, Retinol-binding protein 1SARDH_RAT, Sarcosine dehydrogenase_mitochondrialSPA3N_RAT, Serine protease inhibitor A3NUB2D2_RAT, Ubiquitin-conjugating enzyme E2 D2

Identifiers

PMID27579339
PMCPMC4992036
OpenAlexW2503263107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.