Evidence map›Paper›PMID 27579185›Full record

ArticleCase reports in cardiology2016

Adult ADHD Medications and Their Cardiovascular Implications.

A Sinha, O Lewis, R Kumar, S L H Yeruva, B H Curry

Open access · goldAbstract read
In one paragraph

Article in Case reports in cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

A SinhaDivision of Cardiology, Saint Luke's University Health Network, 801 Ostrum Street, Bethlehem, PA 18015, USA.ORCID 0000-0001-9404-1679
O LewisDivision of Pulmonary Medicine, Department of Internal Medicine, Howard University Hospital, 2041 Georgia Avenue, Washington, DC 20060, USA.
R KumarDepartment of Internal Medicine, Howard University Hospital, 2041 Georgia Avenue, Washington, DC 20060, USA.ORCID 0000-0001-7244-4688
S L H YeruvaDivision of Hematology & Oncology, Department of Internal Medicine, Howard University Hospital, 2041 Georgia Avenue, Washington, DC 20060, USA.ORCID 0000-0001-8937-0662
B H CurryDivision of Cardiology, Howard University Hospital, 2041 Georgia Avenue, Washington, DC 20060, USA.ORCID 0000-0003-3456-6937
Howard University Hospital · USSt. Luke's University Health Network · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurobiological disorder exhibited by difficulty maintaining attention, as well as hyperactivity and impulsive behavior. Central nervous system (CNS) stimulants are the first line of treatment for ADHD. With the increase in number of adults on CNS stimulants, the question that arises is how well do we understand the long-term cardiovascular effects of these drugs. There has been increasing concern that adults with ADHD are at greater risk for developing adverse cardiovascular events such as sudden death, myocardial infarction, and stroke as compared to pediatric population. Cardiovascular response attributed to ADHD medication has mainly been observed in heart rate and blood pressure elevations, while less is known about the etiology of rare cardiovascular events like acute myocardial infarction (AMI), arrhythmia, and cardiomyopathy and its long-term sequelae. We present a unique case of AMI in an adult taking Adderall (mixed amphetamine salts) and briefly discuss the literature relevant to the cardiovascular safety of CNS stimulants for adult ADHD.

Identifiers

PMID27579185
PMCPMC4992783
OpenAlexW2508294741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.