Evidence map›Paper›PMID 27579040›Full record

ArticleCase reports in medicine2016

IL-6-Producing, Noncatecholamines Secreting Pheochromocytoma Presenting as Fever of Unknown Origin.

Marco Ciacciarelli, Davide Bellini, Andrea Laghi, Alessandro Polidoro, Antonio Pacelli, Anna Giulia Bottaccioli, Giuseppina Palmaccio, Federica Stefanelli, Piera Clemenzi, Luisa Carini and 2 more

Open access · goldAbstract read
In one paragraph

Article in Case reports in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Unicentric Castleman Disease and Pheochromocytoma.European journal of case reports in internal medicine · 2022
    Article
  6. Pheochromocytoma with fever and iron deficiency anemia.Proceedings (Baylor University. Medical Center) · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Marco CiacciarelliDepartment of Medico-Surgical Sciences and Biotechnologies, Internal Medicine Unit, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana 34, 04100 Latina, Italy.ORCID 0000-0001-7523-0191
Davide BelliniDepartment of Radiological Sciences, Oncology and Pathology, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana 34, 04100 Latina, Italy.
Andrea LaghiDepartment of Radiological Sciences, Oncology and Pathology, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana 34, 04100 Latina, Italy.
Alessandro PolidoroDepartment of Medico-Surgical Sciences and Biotechnologies, Internal Medicine Unit, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana 34, 04100 Latina, Italy.
Antonio PacelliDepartment of Medico-Surgical Sciences and Biotechnologies, Internal Medicine Unit, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana 34, 04100 Latina, Italy.
Anna Giulia BottaccioliDepartment of Medico-Surgical Sciences and Biotechnologies, Internal Medicine Unit, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana 34, 04100 Latina, Italy.
Giuseppina PalmaccioDepartment of Medico-Surgical Sciences and Biotechnologies, Internal Medicine Unit, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana 34, 04100 Latina, Italy.
Federica StefanelliDepartment of Medico-Surgical Sciences and Biotechnologies, Internal Medicine Unit, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana 34, 04100 Latina, Italy.
Piera ClemenziDepartment of Medico-Surgical Sciences and Biotechnologies, Internal Medicine Unit, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana 34, 04100 Latina, Italy.
Luisa CariniDepartment of Medico-Surgical Sciences and Biotechnologies, Internal Medicine Unit, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana 34, 04100 Latina, Italy.
Luigi IulianoDepartment of Medico-Surgical Sciences and Biotechnologies, Internal Medicine Unit, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana 34, 04100 Latina, Italy.ORCID 0000-0002-0027-9326
Cesare AlessandriDepartment of Medico-Surgical Sciences and Biotechnologies, Internal Medicine Unit, ICOT Hospital, "Sapienza" University of Rome, Via Franco Faggiana 34, 04100 Latina, Italy.
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fever of unknown origin (FUO) can be an unusual first clinical manifestation of pheochromocytoma. Pheochromocytomas are tumors that may produce a variety of substances in addition to catecholamines. To date, several cases of IL-6-producing pheochromocytomas have been reported. This report describes a 45-year-old woman with pheochromocytoma who was admitted with FUO, normal blood pressure levels, microcytic and hypochromic anemia, thrombocytosis, hyperfibrinogenemia, hypoalbuminemia, and normal levels of urine and plasma metanephrines. After adrenalectomy, fever and all inflammatory findings disappeared.

Identifiers

PMID27579040
PMCPMC4992526
OpenAlexW2492170637

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.