Evidence map›Paper›PMID 27578506›Full record

ArticleAnnals of laboratory medicine2016

Prevalence of Major Methicillin-Resistant Staphylococcus aureus Clones in Korea Between 2001 and 2008.

Gi Su Kang, Yung Hee Jung, Hwa Su Kim, Yeong Seon Lee, Chan Park, Kwang Jun Lee, Jeong Ok Cha

Open access · diamondAbstract read
In one paragraph

Article in Annals of laboratory medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  5. Performance Evaluation of the IR BiotyperAntibiotics (Basel, Switzerland) · 2022
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  8. Molecular Characterization ofInfection and drug resistance · 2021
    Article
  9. Article
  10. Review
  11. Impact of Community-Onset Methicillin-ResistantAnnals of laboratory medicine · 2019
    Article
  12. Genomic surveillance of methicillin-resistantWestern Pacific surveillance and response journal : WPSAR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Gi Su KangDivision of Antimicrobial Resistance, Center for Infectious Disease, National Research Institute of Health, Centers for Disease Control and Prevention (KCDC), Cheongju, Korea.
Yung Hee JungDivision of Antimicrobial Resistance, Center for Infectious Disease, National Research Institute of Health, Centers for Disease Control and Prevention (KCDC), Cheongju, Korea.
Hwa Su KimDivision of Antimicrobial Resistance, Center for Infectious Disease, National Research Institute of Health, Centers for Disease Control and Prevention (KCDC), Cheongju, Korea.
Yeong Seon LeeDivision of Antimicrobial Resistance, Center for Infectious Disease, National Research Institute of Health, Centers for Disease Control and Prevention (KCDC), Cheongju, Korea.
Chan ParkDivision of Antimicrobial Resistance, Center for Infectious Disease, National Research Institute of Health, Centers for Disease Control and Prevention (KCDC), Cheongju, Korea.
Kwang Jun LeeDivision of Antimicrobial Resistance, Center for Infectious Disease, National Research Institute of Health, Centers for Disease Control and Prevention (KCDC), Cheongju, Korea.
Jeong Ok ChaDivision of Antimicrobial Resistance, Center for Infectious Disease, National Research Institute of Health, Centers for Disease Control and Prevention (KCDC), Cheongju, Korea. jeongok22@gmail.com.
Korea Center for Disease Control and Prevention · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMethicillin-resistant Staphylococcus aureus (MRSA) are important pathogens causing nosocomial infections in Korean hospitals. This study aimed to investigate the epidemiological and genetic diversity of clinical S. aureus isolates in healthcare settings from 2001 to 2008.

methodsSamples and data were obtained from 986 individuals as part of the National Antimicrobial Surveillance Project, involving 10 regions nationwide. Molecular typing studies, including multilocus sequence typing (MLST) and staphylococcal cassette chromosome mec (SCCmec) typing were performed, and a representative clone of Korean MRSA was classified by combinational grouping using a DiversiLab (DL; bioMérieux, France) repetitive element polymerase chain reaction (rep-PCR) system.

resultsNine Korean MRSA clones (KMRSA-1 to -9) were identified by analysis of genetic backgrounds and molecular characteristics. KMRSA-1 to -3, expressing clonal complex (CC) 5 (carrying SCCmec II), CC8 (carrying SCCmec III), and CC72 (carrying SCCmec IV) were spread nationwide. In contrast, KMRSA-6 was highly prevalent in Gyeongsangnam-do, and KMRSA-4 was highly prevalent in Jeollanam-do and Jeollabuk-do.

conclusionsEpidemic KMRSA clones were genetically similar to major clones identified from the USA, with the exception of KMRSA-2, which had the SCCmec III type. Our results provide important insights into the distribution and molecular genetics of MRSA strains in Korea and may aid in the monitoring of MRSA spread throughout the country.

Indexed as

Bacterial ProteinsDNA, BacterialElectrophoresis, Gel, Pulsed-FieldHospitalsHumansMethicillin-Resistant Staphylococcus aureusMultilocus Sequence TypingMultiplex Polymerase Chain ReactionPrevalenceRepublic of KoreaStaphylococcal InfectionsBacterial ProteinsDNA, BacterialDiversiLabGenetic diversityKorean MRSA clonesMultilocus sequence typing

Identifiers

PMID27578506
PMCPMC5011106
OpenAlexW2512433452

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.