Evidence map›Paper›PMID 27578048›Full record

ReviewTranslational stroke research2017

Translational MR Neuroimaging of Stroke and Recovery.

Emiri T Mandeville, Cenk Ayata, Yi Zheng, Joseph B Mandeville

Abstract readReview
In one paragraph

Review in Translational stroke research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Emiri T MandevilleNeuroprotection Research Laboratory, Massachusetts General Hospital, Charlestown, MA, USA. etm@nmr.mgh.harvard.edu.
Cenk AyataNeurovascular Research Laboratory, Massachusetts General Hospital, Charlestown, MA, USA.
Yi ZhengNeurovascular Research Laboratory, Massachusetts General Hospital, Charlestown, MA, USA.
Joseph B MandevilleAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA.
Massachusetts General Hospital · US

Funding

Targeting ROCK for Neurogliovascular Plasticity & Remodeling After StrokeP01NS055104 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI LO, ENG H. · 2007 to 2018
$13.3M
NINDS NIH HHS P01 NS055104
6 · The paper itself

Abstract

Multiparametric magnetic resonance imaging (MRI) has become a critical clinical tool for diagnosing focal ischemic stroke severity, staging treatment, and predicting outcome. Imaging during the acute phase focuses on tissue viability in the stroke vicinity, while imaging during recovery requires the evaluation of distributed structural and functional connectivity. Preclinical MRI of experimental stroke models provides validation of non-invasive biomarkers in terms of cellular and molecular mechanisms, while also providing a translational platform for evaluation of prospective therapies. This brief review of translational stroke imaging discusses the acute to chronic imaging transition, the principles underlying common MRI methods employed in stroke research, and the experimental results obtained by clinical and preclinical imaging to determine tissue viability, vascular remodeling, structural connectivity of major white matter tracts, and functional connectivity using task-based and resting-state fMRI during the stroke recovery process.

Indexed as

Translational Research, BiomedicalAnimalsBrainBrain IschemiaBrain MappingDiffusion Magnetic Resonance ImagingHumansMagnetic Resonance ImagingNeovascularization, PathologicNeuroimagingPositron-Emission TomographyRecovery of FunctionStrokeClinicalExperimentalImagingMRIPETStroke

Identifiers

PMID27578048
PMCPMC5243530
OpenAlexW2518000016

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.