Evidence map›Paper›PMID 27578046›Full record

ArticleEuropean radiology2017

Combined MR direct thrombus imaging and non-contrast magnetic resonance venography reveal the evolution of deep vein thrombosis: a feasibility study.

I A Mendichovszky, A N Priest, D J Bowden, S Hunter, I Joubert, S Hilborne, M J Graves, T Baglin, D J Lomas

Registry-linked trialOpen access · hybridAbstract readEvaluation Study
In one paragraph

Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04732299 (Staging Diagnosis and Prognosis of Lower Extremity Deep Venous Thrombosis Based on Magnetic Resonance Imaging), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04732299 unknown statusnot on this mapstarted 2021, after this paper: background citation

Staging Diagnosis and Prognosis of Lower Extremity Deep Venous Thrombosis Based on Magnetic Resonance Imaging: a Prospective Study

Typeobservational_patient_registrySponsorFirst Affiliated Hospital Xi'an Jiaotong UniversityRan2021 to 2024Enrolled60ConditionsVenous ThrombosisArmsMRI examination
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Diffusion weighted cardiovascular magnetic resonance imaging for discriminating acute from non-acute deep venous Thrombus.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2019
    Article
  9. Pelvic cardiovascular magnetic resonance venography: venous changes with patient position and hydration status.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2019
    Article
  10. Usefulness of non-contrast-enhanced magnetic resonance imaging prior to venous interventions.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2019
    Article
  11. Cardiovascular magnetic resonance black-blood thrombus imaging for the diagnosis of acute deep vein thrombosis at 1.5 Tesla.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2018
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

I A MendichovszkyDepartment of Radiology, Addenbrooke's Hospital, Cambridge, UK. im391@cam.ac.uk.
A N PriestDepartment of Radiology, Addenbrooke's Hospital, Cambridge, UK.
D J BowdenDepartment of Radiology, Addenbrooke's Hospital, Cambridge, UK.
S HunterDepartment of Radiology, Addenbrooke's Hospital, Cambridge, UK.
I JoubertDepartment of Radiology, Addenbrooke's Hospital, Cambridge, UK.
S HilborneDepartment of Radiology, Addenbrooke's Hospital, Cambridge, UK.
M J GravesDepartment of Radiology, Addenbrooke's Hospital, Cambridge, UK.
T BaglinDepartment of Haematology, Addenbrooke's Hospital, Cambridge, UK.
D J LomasDepartment of Radiology, Addenbrooke's Hospital, Cambridge, UK.
Addenbrooke's Hospital · GBUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesLower limb deep venous thrombosis (DVT) is a common condition with high morbidity and mortality. The aim of the study was to investigate the temporal evolution of the acute thrombus by magnetic resonance imaging (MRI) and its relationship to venous recanalization in patients with recurrent DVTs.

methodsThirteen patients with newly diagnosed lower limb DVTs underwent MRI with non-contrast MR venography (NC-MRV) and MR direct thrombus imaging (MR-DTI), an inversion-recovery water-selective fast gradient-echo acquisition. Imaging was performed within 7 days of the acute thrombotic event, then at 3 and 6 months.

resultsBy 3 months from the thrombotic event a third of the thrombi had resolved and by 6 months about half of the cases had resolved on the basis of vein recanalisation using NC-MRV. On the initial MR-DTI acute thrombus was clearly depicted by hyperintense signal, while the remaining thrombi were predominantly low signal at 3 and 6 months. Some residual thrombi contained small and fragmented persisting hyperintense areas at 3 months, clearing almost completely by 6 months.

conclusionsOur study suggests that synergistic venous assessment with combined NC-MRV and MR-DTI is able to distinguish acute venous thrombosis from the established (old) or evolving DVT detected by ultrasound. KEY POINTS: • MRI can distinguish between acute and evolving or chronic lower limb DVT • Two advanced MRI techniques can follow the evolution of lower limb DVT • MRI could be used to avoid an incorrect diagnosis of recurrent DVT • MRI could help avoid the risks and complications of lifelong anticoagulation therapy.

Indexed as

Acute DiseaseAdolescentAdultAgedFeasibility StudiesFemaleHumansLower ExtremityMagnetic Resonance AngiographyMagnetic Resonance SpectroscopyMaleMiddle AgedMultimodal ImagingPhlebographyPopliteal VeinRecurrenceClinical decision-makingDiagnosisLongitudinal studyMagnetic resonance imagingVenous thrombosis

Identifiers

PMID27578046
PMCPMC5409804
OpenAlexW2510685648

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.