ArticleBMC microbiology2016
Diversity of Clostridium perfringens toxin-genotypes from dairy farms.
Article in BMC microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed, 43 citations in OpenAlex.
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- Seroprevalence, isolation, comprehensive characterization, and pathogenicity of Clostridium perfringens strain from yak in Xizang, China.Scientific reports · 2026Article
- Preventive effect of matrine on clostridium perfringens type A-induced diarrhoea in piglets.Veterinary research communications · 2025Article
- Genetic diversity and phylogenetic relationships of Clostridium perfringens strains isolated from mastitis and enteritis in Egyptian dairy farms.BMC microbiology · 2024Article
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- Identification and Characterization ofToxins · 2022Article
- A global phylogenomic and metabolic reconstruction of the large intestine bacterial community of domesticated cattle.Microbiome · 2022Article
- FI: The Fecobiome Initiative.Foodborne pathogens and disease · 2022Article
- Phenotypic and Genotypic Characterization ofVeterinary sciences · 2022Article
- Toxigenic Profile ofComparative medicine · 2022Article
- Infection Dynamics ofFrontiers in veterinary science · 2022Article
- Bacteriological and molecular typing of Clostridium perfringens strains isolated in retail beef in Beijing, China.The Journal of veterinary medical science · 2021Article
- Innovative and Highly Sensitive Detection ofToxins · 2021Article
- Prevalence and Genetic Diversity ofInfection and drug resistance · 2021Article
- Molecular Characterization ofToxins · 2020Article
- Prevalence and multilocus sequence typing of Clostridium perfringens isolated from 4 duck farms in Shandong province, China.Poultry science · 2020Article
- Review
- Characterization ofInternational journal of environmental research and public health · 2020Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundClostridium (C.) perfringens is the causative agent of several diseases in animals and humans, including histotoxic and enteric infections. To gain more insight into the occurrence of its different toxin-genotypes in dairy herds, including those toxin genes previously associated with diseases in cattle or humans, 662 isolates cultivated from feces, rumen content and feed collected from 139 dairy farms were characterized by PCR (detecting cpa, cpb, iap, etx, cpe, and both allelic variants of cpb2).
resultsIsolates from feces were assigned to type A (cpa positive, n = 442) and D (cpa and etx positive, n = 2). Those from rumen content (n = 207) and feed (n = 13) were all assigned to type A. The consensus and atypical variants of the cpb2 gene were detected in 64 (14.5 %) and 138 (31.22 %) of all isolates from feces, and 30 (14.5 %) and 54 (26.1 %) of all isolates from rumen content, respectively.
conclusionBoth allelic variants of cpb2 occurred frequently in animals without signs of acute enteric disease, whereby the atypical variant dominated. Five (0.8 %) of all type A isolates were positive for the cpe gene. Therefore, the present study indicates that dairy cows are no primary source for potentially human pathogenic enterotoxin gene positive strains.
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