ArticleBMC cardiovascular disorders2016
Ischemic aetiology, self-reported frailty, and gender with respect to cognitive impairment in chronic heart failure patients.
Article in BMC cardiovascular disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Prevalence and associated factors of cognitive frailty in older adults with heart failure: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Cognition and Frailty in Patients With Heart Failure: A Systematic Review of the Association Between Frailty and Cognitive Impairment.Frontiers in psychiatry · 2021Pooled it
- Impact of Frailty on Mortality and Hospitalization in Chronic Heart Failure: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2018Pooled it
- Exploring the Relationship Between Sleep Disturbances, Gut Microbiota, and Cognition in Patients with Heart Failure: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2026Article
- Females and Exercise Capacity Impairment in Heart Failure: A Sex-Focused Analysis.Journal of cardiovascular development and disease · 2025Article
- Factors Influencing the Development and Severity of Cognitive Decline in Patients with Chronic Heart Failure.Medicina (Kaunas, Lithuania) · 2024Article
- Soluble Transferrin Receptor as Iron Deficiency Biomarker: Impact on Exercise Capacity in Heart Failure Patients.Journal of personalized medicine · 2023Article
- Psychosocial factors partially explain gender differences in health-related quality of life in heart failure patients.ESC heart failure · 2023Observational
- Effect of cognitive impairment at admission on activities of daily living at discharge in older patients with heart failure.Japanese journal of comprehensive rehabilitation science · 2023Article
- Risk evaluation of cognitive impairment in patients with heart failure: A call for action.International journal of cardiology. Heart & vasculature · 2022Article
- Adherence to Immunosuppressive Therapies after Kidney Transplantation from a Biopsychosocial Perspective: A Cross-Sectional Study.Journal of clinical medicine · 2022Article
- Cognitive Impairment in Heart Failure-A Review.Biology · 2022Review
- Determinants of the survival benefit associated with statins in patients with acute heart failure.ESC heart failure · 2021Article
- Blood Differential Gene Expression in Patients with Chronic Heart Failure and Systemic Iron Deficiency: Pathways Involved in Pathophysiology and Impact on Clinical Outcomes.Journal of clinical medicine · 2021Article
- Frailty in Wild-Type Transthyretin Cardiac Amyloidosis: The Tip of the Iceberg.Journal of clinical medicine · 2021Article
- Operationalizing Social Environments in Cognitive Aging and Dementia Research: A Scoping Review.International journal of environmental research and public health · 2021Article
- Cognitive impairment in patients hospitalized for congestive heart failure: data from the RICA Registry.Internal and emergency medicine · 2021Article
- Combined Influence of Depression and Physical Frailty on Cognitive Impairment in Patients with Heart Failure.International journal of environmental research and public health · 2018Article
- Gender Differences in the Impact of Cognitive Function on Health Literacy among Older Adults with Heart Failure.International journal of environmental research and public health · 2018Article
- Physical Frailty and Cognitive Functioning in Korea Rural Community-Dwelling Older Adults.Journal of clinical medicine · 2018Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDecisive information on the parameters involved in cognitive impairment in patients with chronic heart failure is as yet lacking. Our aim was to determine the functional and psychosocial variables related with cognitive impairment using the mini-mental-state examination (MMSE) with age-and education-corrected scores.
methodsA cohort study of chronic heart failure patients included in an integrated multidisciplinary hospital/primary care program. The MMSE (corrected for age and education in the Spanish population) was administered at enrolment in the program. Analyses were performed in 525 patients. Demographic and clinical variables were collected. Comprehensive assessment included depression (Yesavage), family function (family APGAR), social network (Duke), dependence (Barthel Index), frailty (Barber), and comorbidities. Univariate and multivariate logistic regression were performed to determine the predictors of cognitive impairment.
resultsCognitive impairment affected 145 patients (27.6 %). Explanatory factors were gender (OR: 2.77 (1.75-4.39) p < 0.001), ischemic etiology (OR: 1.99 (1.25-3.17) p = 0.004), frailty (OR: 1.58 (0.99 to 2.50, p =0.050), albumin > 3.5 (OR: 0.59 (0.35-0.99) p = 0.048), and beta-blocker treatment (OR: 0.36 (0.17 to 0.76, p = 0.007)). No association was found between cognitive impairment and social support or family function.
conclusionThe observed prevalence of cognitive impairment using MMSE corrected scores was 27.6 %. A global approach in the management of these patients is needed, especially focusing on women and patients with frailty, low albumin levels, and ischemic aetiology heart failure.
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