ReviewBiomedical engineering online2016
Current methodological and technical limitations of time and volumetric capnography in newborns.
Review in Biomedical engineering online, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03758313 (Non-Invasive Monitoring of Partial Pressure of Carbon Dioxide in Mechanically Ventilated Preterm Infants), which is not on this map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Non-Invasive Monitoring of Partial Pressure of Carbon Dioxide in Mechanically Ventilated Preterm Infants
Who cites it
20 citing papers in PubMed.
- Evaluation of accuracy, filter performance, and durability among capnography sampling lines: a bench study.Journal of clinical monitoring and computing · 2026Article
- Seeing beyond the numbers: capnography as a vital tool in pediatric emergency care.International journal of emergency medicine · 2026Review
- Exhaled Carbon Dioxide Monitoring Using Instantaneous COPediatric pulmonology · 2025Article
- High PEEP Increases Airway Dead Space and Decreases Alveolar Ventilation: A New Technique for Volumetric Capnography.Biomedicines · 2025Article
- Respiratory Function in Ventilated Newborn Infants Nursed Prone and Supine.Pediatric pulmonology · 2025Observational
- Chest Radiography Scores for Predicting the Severity of Respiratory Status in Newborns Weighing More Than 1,500 g.Cureus · 2025Article
- Development and preliminary tests of a portable volumetric capnograph for outpatient use.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025Article
- Enhancing the estimation of PaCOBiomedical engineering online · 2024Article
- Article
- Review
- Functional morphometry: non-invasive estimation of the alveolar surface area in extremely preterm infants.Pediatric research · 2023Article
- Capnodynamics - noninvasive cardiac output and mixed venous oxygen saturation monitoring in children.Frontiers in pediatrics · 2023Review
- Assessment of neonatal respiratory rate variability.Journal of clinical monitoring and computing · 2022Article
- ERS International Congress 2021: highlights from the Paediatric Assembly.ERJ open research · 2022Review
- Accuracy of a battery-powered portable capnometer in premature infants.Journal of clinical monitoring and computing · 2022Article
- Novel volumetric capnography indices measure ventilation inhomogeneity in cystic fibrosis.ERJ open research · 2022Article
- End-tidal capnography monitoring in infants ventilated on the neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Reduction in minute alveolar ventilation causes hypercapnia in ventilated neonates with respiratory distress.European journal of pediatrics · 2021Article
- Respiratory Care for the Ventilated Neonate.Canadian respiratory journal · 2018Review
- Article
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although capnography is a standard tool in mechanically ventilated adult and pediatric patients, it has physiological and technical limitations in neonates. Gas exchange differs between small and adult lungs due to the greater impact of small airways on gas exchange, the higher impact of the apparatus dead space on measurements due to lower tidal volume and the occurrence of air leaks in intubated patients. The high respiratory rate and low tidal volume in newborns, especially those with stiff lungs, require main-stream sensors with fast response times and minimal dead-space or low suction flow when using side-stream measurements. If these technical requirements are not fulfilled, the measured end-tidal CO2 (P et CO 2 ), which should reflect the alveolar CO2 and the calculated airway dead spaces, can be misleading. The aim of this survey is to highlight the current limitations of capnography in very young patients to avoid pitfalls associated with the interpretation of capnographic parameters, and to describe further developments.
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