Evidence map›Paper›PMID 27576363›Full record

ArticleInternational journal of hygiene and environmental health2017

The exposome in practice: Design of the EXPOsOMICS project.

P Vineis, M Chadeau-Hyam, H Gmuender, J Gulliver, Z Herceg, J Kleinjans, M Kogevinas, S Kyrtopoulos, M Nieuwenhuijsen, D H Phillips and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in International journal of hygiene and environmental health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07422090 (Prevention of Suicidal Behavior Through Therapeutic Interventions Guided by Digital Phenotype and Pharmacogenetics), which is not on this map. Cited by 128 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07422090 recruitingnot on this mapstarted 2025, after this paper: background citation

Prevention of Suicidal Behavior Through Therapeutic Interventions Guided by Digital Phenotype and Pharmacogenetics: The SMARTomicS Study Protocol

TypeobservationalSponsorInstituto de Investigación Sanitaria de la Fundación Jiménez DíazRan2025 to 2028Enrolled5,000ConditionsSuicide AttemptArmsNo Intervention: Observational Cohort
3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Associations between the built environment and obesity: an umbrella review.International journal of health geographics · 2021
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Fine Particulate Matter (PM2.5), the Exposome, and Cumulative Health Risk: A Life-course Perspective.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2026
    Review
  13. Article
  14. Article
  15. Article
  16. Association of age-related macular degeneration with exposome related metabolomics.Metabolomics : Official journal of the Metabolomic Society · 2026
    Article
  17. Article
  18. Review
  19. Review
  20. Article

68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

P VineisMRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, UK. Electronic address: p.vineis@imperial.ac.uk.
M Chadeau-HyamMRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, UK.
H GmuenderGenedata AG, Basel, Switzerland.
J GulliverMRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, UK.
Z HercegInternational Agency for Research on Cancer (IARC), Lyon, France.
J KleinjansMaastricht University, Department of Health Risk Analysis and Toxicology, Maastricht, Netherlands.
M KogevinasBarcelona Institute for Global Health (ISGlobal), Barcelona, Spain.
S KyrtopoulosNational Hellenic Research Foundation, Institute of Biology, Medicinal Chemistry and Biotechnology, Division of Organic and Medicinal Chemistry, Athens, Greece.
M NieuwenhuijsenBarcelona Institute for Global Health (ISGlobal), Barcelona, Spain.
D H PhillipsKing's College London, Analytical and Environmental Sciences Division, MRC-PHE Centre for Environment and Health, London, UK.
N Probst-HenschSwiss Tropical School of Public Health, Department of Epidemiology and Public Health, Basel, Switzerland and University of Basel, Basel, Switzerland.
A ScalbertInternational Agency for Research on Cancer (IARC), Lyon, France.
R VermeulenUtrecht University, Institute for Risk Assessment Sciences, Environmental Epidemiology Division, Utrecht, Netherlands.
C P WildInternational Agency for Research on Cancer (IARC), Lyon, France.
EXPOsOMICS Consortium

Funding

Cancer Research UK 14329World Health Organization 001
6 · The paper itself

Abstract

EXPOsOMICS is a European Union funded project that aims to develop a novel approach to the assessment of exposure to high priority environmental pollutants, by characterizing the external and the internal components of the exposome. It focuses on air and water contaminants during critical periods of life. To this end, the project centres on 1) exposure assessment at the personal and population levels within existing European short and long-term population studies, exploiting available tools and methods which have been developed for personal exposure monitoring (PEM); and 2) multiple "omic" technologies for the analysis of biological samples (internal markers of external exposures). The search for the relationships between external exposures and global profiles of molecular features in the same individuals constitutes a novel advancement towards the development of "next generation exposure assessment" for environmental chemicals and their mixtures. The linkage with disease risks opens the way to what are defined here as 'exposome-wide association studies' (EWAS).

Indexed as

Air PollutionWater PollutionAdultBiomarkersChildEnvironmental MonitoringEuropeGenomicsHumansResearch DesignRisk AssessmentBiomarkers

Identifiers

PMID27576363
PMCPMC6192011

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.