Evidence map›Paper›PMID 27576245›Full record

ArticleIEEE transactions on medical imaging2017

Cone Beam X-ray Luminescence Computed Tomography Based on Bayesian Method.

Guanglei Zhang, Fei Liu, Jie Liu, Jianwen Luo, Yaoqin Xie, Jing Bai, Lei Xing

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Superfast Scan of Focused X-Ray Luminescence Computed Tomography Imaging.IEEE access : practical innovations, open solutions · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Focused x-ray luminescence computed tomography: experimental studies.Proceedings of SPIE--the International Society for Optical Engineering · 2019
    Article
  10. Regularized reconstruction based on joint LBiomedical optics express · 2019
    Article
  11. Recent methodology advances in fluorescence molecular tomography.Visual computing for industry, biomedicine, and art · 2018
    Review
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Guanglei Zhang
Fei Liu
Jie Liu
Jianwen Luo
Yaoqin Xie
Jing Bai
Lei Xing
Beijing Jiaotong University · CNTsinghua University · CNShenzhen Institutes of Advanced Technology · CNStanford University · US

Funding

Computational Tools for Next Generation Volumetric Cone Beam Computed TomographyR01EB016777 · NIBIB · STANFORD UNIVERSITY · PI XING, LEI · 2013 to 2016
$2.1M
NIBIB NIH HHS R01 EB016777
6 · The paper itself

Abstract

X-ray luminescence computed tomography (XLCT), which aims to achieve molecular and functional imaging by X-rays, has recently been proposed as a new imaging modality. Combining the principles of X-ray excitation of luminescence-based probes and optical signal detection, XLCT naturally fuses functional and anatomical images and provides complementary information for a wide range of applications in biomedical research. In order to improve the data acquisition efficiency of previously developed narrow-beam XLCT, a cone beam XLCT (CB-XLCT) mode is adopted here to take advantage of the useful geometric features of cone beam excitation. Practically, a major hurdle in using cone beam X-ray for XLCT is that the inverse problem here is seriously ill-conditioned, hindering us to achieve good image quality. In this paper, we propose a novel Bayesian method to tackle the bottleneck in CB-XLCT reconstruction. The method utilizes a local regularization strategy based on Gaussian Markov random field to mitigate the ill-conditioness of CB-XLCT. An alternating optimization scheme is then used to automatically calculate all the unknown hyperparameters while an iterative coordinate descent algorithm is adopted to reconstruct the image with a voxel-based closed-form solution. Results of numerical simulations and mouse experiments show that the self-adaptive Bayesian method significantly improves the CB-XLCT image quality as compared with conventional methods.

Indexed as

Cone-Beam Computed TomographyAlgorithmsAnimalsBayes TheoremImage Processing, Computer-AssistedLuminescenceMicePhantoms, ImagingTomography, X-Ray ComputedX-Rays

Identifiers

PMID27576245
PMCPMC5391999
OpenAlexW2507291501

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.