ReviewJournal of the American Chemical Society2016
Activation of Dioxygen by Iron and Manganese Complexes: A Heme and Nonheme Perspective.
Review in Journal of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
75 citing papers in PubMed, 305 citations in OpenAlex.
- Evidence for the Formation of an Iron(III)-Indolenylperoxo Intermediate During Indole Dioxygenation: Similarities with Heme Dioxygenases.Inorganic chemistry · 2026Article
- A Structurally Analogous Series of Mn(II), Fe(II), and Co(II) Complexes Which Exhibit Three Distinct Reactivities with Dioxygen.Inorganic chemistry · 2026Article
- Review
- Steric Mapping, Ligand Dynamics, and Cycloisomerization Catalysis with Redox Robust MnOrganometallics · 2026Article
- A mononuclear nonheme iron complex with higher affinity for ONature communications · 2026Article
- Dynamic metal coordination controls chemoselectivity in a radical halogenase.Nature chemical biology · 2026Article
- Article
- Electronic Structure Contributions to the Reactivity of Mononuclear FeAccounts of chemical research · 2026Article
- A versatile bioinspired iron-based catalyst for the C-H bond and alcohol oxidations.Scientific reports · 2025Article
- Promiscuity in Molecular Mimics of the Cysteine Dioxygenase: Effects of Selenium in the Substrate and Cobalt as the Central Metal Ion.Angewandte Chemie (International ed. in English) · 2025Article
- Iron(III)-Mediated C-H Alkylation: One-Electron Differentiation Increases Activity and Chemoselectivity.Journal of the American Chemical Society · 2025Article
- Heme/NADH Mimics Co-Decorated Allosteric Capsules for Regulating Oxygen Activation and Upregulating Intracellular Methionine Depletion.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A Transient, Highly Reactive Fe(IV)=O Species Revealed Through the Interference by OACS catalysis · 2025Article
- Activation of Molecular Oxygen and Selective Oxidation with Metal Complexes.Accounts of chemical research · 2025Article
- Influence of the second coordination sphere on OJournal of inorganic biochemistry · 2025Article
- Experimental electronic structures of the FeProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Electron transfer in biological systems.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024Review
- Bioinspired recognition in metal-organic frameworks enabling precise sieving separation of fluorinated propylene and propane mixtures.Nature communications · 2024Article
- The [(Bn-tpen)FeMolecules (Basel, Switzerland) · 2024Article
- Fresh Impetus in the Chemistry of Calcium Peroxides.Journal of the American Chemical Society · 2024Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The rational design of well-defined, first-row transition metal complexes that can activate dioxygen has been a challenging goal for the synthetic inorganic chemist. The activation of O2 is important in part because of its central role in the functioning of metalloenzymes, which utilize O2 to perform a number of challenging reactions including the highly selective oxidation of various substrates. There is also great interest in utilizing O2, an abundant and environmentally benign oxidant, in synthetic catalytic oxidation systems. This Perspective brings together recent examples of biomimetic Fe and Mn complexes that can activate O2 in heme or nonheme-type ligand environments. The use of oxidants such as hypervalent iodine (e.g., ArIO), peracids (e.g., m-CPBA), peroxides (e.g., H2O2) or even superoxide is a popular choice for accessing well-characterized metal-superoxo, metal-peroxo, or metal-oxo species, but the instances of biomimetic Fe/Mn complexes that react with dioxygen to yield such observable metal-oxygen species are surprisingly few. This Perspective focuses on mononuclear Fe and Mn complexes that exhibit reactivity with O2 and lead to spectroscopically observable metal-oxygen species, and/or oxidize biologically relevant substrates. Analysis of these examples reveals that solvent, spin state, redox potential, external co-reductants, and ligand architecture can all play important roles in the O2 activation process.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.