Evidence map›Paper›PMID 27576077›Full record

ArticleVaccine2016

Re-designing the Mozambique vaccine supply chain to improve access to vaccines.

Bruce Y Lee, Leila A Haidari, Wendy Prosser, Diana L Connor, Ruth Bechtel, Amelia Dipuve, Hidayat Kassim, Balbina Khanlawia, Shawn T Brown

Abstract read
In one paragraph

Article in Vaccine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. COVID-19 vaccine distribution planning using a congested queuing system-A real case from Australia.Transportation research. Part E, Logistics and transportation review · 2022
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  18. A light-touch routing optimization tool (RoOT) for vaccine and medical supply distribution in Mozambique.International transactions in operational research : a journal of The International Federation of Operational Research Societies · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bruce Y LeePublic Health Computational and Operations Research (PHICOR) and Global Obesity Prevention Center (GOPC), Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: brucelee@jhu.edu.
Leila A HaidariPittsburgh Supercomputer Center, Carnegie Mellon University, Pittsburgh, PA, USA.
Wendy ProsserVillageReach, Seattle, WA, USA.
Diana L ConnorPublic Health Computational and Operations Research (PHICOR) and Global Obesity Prevention Center (GOPC), Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Ruth BechtelVillageReach, Seattle, WA, USA.
Amelia DipuveProvincial Directorate of Health, Gaza, Mozambique.
Hidayat KassimProvincial Directorate of Health, Cabo Delgado, Mozambique.
Balbina KhanlawiaMozambique Ministry of Health, Maputo, Mozambique.
Shawn T BrownPittsburgh Supercomputer Center, Carnegie Mellon University, Pittsburgh, PA, USA.

Funding

MULTILEVEL SYSTEMS-ORIENTED CHILDHOOD OBESITY STUDY IN CHINAU54HD070725 · NICHD · JOHNS HOPKINS UNIVERSITY · PI WANG, YOUFA · 2011 to 2016
$15.9M
Virtual Population Obesity Prevention (VPOP) Labs: Computational, Multi-Scale Models for Obesity SolutionsU01HD086861 · NICHD · JOHNS HOPKINS UNIVERSITY · PI LEE, BRUCE Y · 2015 to 2019
$2.8M
Regional Healthcare Ecosystem Analyst for Healthcare Associated InfectionsR01HS023317 · AHRQ · JOHNS HOPKINS UNIVERSITY · PI LEE, BRUCE Y · 2014 to 2014
$2.4M
AHRQ HHS R01 HS023317NICHD NIH HHS U01 HD086861NICHD NIH HHS U54 HD070725
6 · The paper itself

Abstract

introductionPopulations and routine childhood vaccine regimens have changed substantially since supply chains were designed in the 1980s, and introducing new vaccines during the "Decade of Vaccine" may exacerbate existing bottlenecks, further inhibiting the flow of all vaccines.

methodsWorking with the Mozambique Ministry of Health, our team implemented a new process that integrated HERMES computational simulation modeling and on-the-ground implementers to evaluate and improve the Mozambique vaccine supply chain using a system-re-design that integrated new supply chain structures, information technology, equipment, personnel, and policies.

resultsThe alternative system design raised vaccine availability (from 66% to 93% in Gaza; from 76% to 84% in Cabo Delgado) and reduced the logistics cost per dose administered (from $0.53 to $0.32 in Gaza; from $0.38 to $0.24 in Cabo Delgado) as compared to the multi-tiered system under the current EPI. The alternative system also produced higher availability at lower costs after new vaccine introductions. Since reviewing scenarios modeling deliveries every two months in the north of Gaza, the provincial directorate has decided to pilot this approach diverging from decades of policies dictating monthly deliveries. DISCUSSION: Re-design improved not only supply chain efficacy but also efficiency, important since resources to deliver vaccines are limited. The Mozambique experience and process can serve as a model for other countries during the Decade of Vaccines. For the Decade of Vaccines, getting vaccines at affordable prices to the market is not enough. Vaccines must reach the population to be successful.

Indexed as

Computer SimulationHealth Services AccessibilityHumansImmunization ProgramsMozambiqueVaccinationVaccinesVaccinesComputational modelingMozambiqueSupply chainVaccines

Identifiers

PMID27576077
PMCPMC5547748

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.