Evidence map›Paper›PMID 27575283›Full record

ReviewNanomedicine : nanotechnology, biology, and medicine2017

Role of metal and metal oxide nanoparticles as diagnostic and therapeutic tools for highly prevalent viral infections.

Tejabhiram Yadavalli, Deepak Shukla

Open access · greenAbstract readReview
In one paragraph

Review in Nanomedicine : nanotechnology, biology, and medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 173 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Cardiovascular Toxicity of Metal-Based Nanoparticles.International journal of molecular sciences · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Cytotoxicity of Laser-Synthesized Nanoparticles of Elemental Bismuth.Bulletin of experimental biology and medicine · 2024
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Tejabhiram YadavalliNanotechnology Research Centre, SRM University, Kattankulathur, India; Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, USA.
Deepak ShuklaDepartment of Ophthalmology and Visual Sciences, University of Illinois at Chicago, USA; Department of Microbiology and Immunology, University of Illinois at Chicago, USA. Electronic address: dshukla@uic.edu.
SRM Institute of Science and Technology · INUniversity of Illinois Chicago · US

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AAKALU, VINAY · 1985 to 2025
$14.8M
Micro-nano Platforms for HSV VaccineR21AI103754 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SHUKLA, DEEPAK · 2013 to 2014
$439k
NEI NIH HHS P30 EY001792NIAID NIH HHS R21 AI103754
6 · The paper itself

Abstract

Nanotechnology is increasingly playing important roles in various fields including virology. The emerging use of metal or metal oxide nanoparticles in virus targeting formulations shows the promise of improved diagnostic or therapeutic ability of the agents while uniquely enhancing the prospects of targeted drug delivery. Although a number of nanoparticles varying in composition, size, shape, and surface properties have been approved for human use, the candidates being tested or approved for clinical diagnosis and treatment of viral infections are relatively less in number. Challenges remain in this domain due to a lack of essential knowledge regarding the in vivo comportment of nanoparticles during viral infections. This review provides a broad overview of recent advances in diagnostic, prophylactic and therapeutic applications of metal and metal oxide nanoparticles in human immunodeficiency virus, hepatitis virus, influenza virus and herpes virus infections. Types of nanoparticles commonly used and their broad applications have been explained in this review.

Indexed as

Drug Delivery SystemsAntiviral AgentsHumansMetal NanoparticlesMetalsNanotechnologyOxidesAntiviral AgentsMetalsOxidesMetal and metal oxideNanoparticleVirus

Identifiers

PMID27575283
PMCPMC5237416
OpenAlexW2516468195

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.