ArticlePLoS biology2016
Short Time-Scale Sensory Coding in S1 during Discrimination of Whisker Vibrotactile Sequences.
Article in PLoS biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- Neural correlates of perceptual decision-making in the primary somatosensory cortex.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Stimulus information guides the emergence of behavior-related signals in primary somatosensory cortex during learning.Cell reports · 2024Article
- Behaviorally relevant decision coding in primary somatosensory cortex neurons.Nature neuroscience · 2022Article
- Ipsilateral Stimulus Encoding in Primary and Secondary Somatosensory Cortex of Awake Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Conveyance of texture signals along a rat whisker.Scientific reports · 2021Article
- Sequence Learning Induces Selectivity to Multiple Task Parameters in Mouse Somatosensory Cortex.Current biology : CB · 2021Article
- A sensory integration account for time perception.PLoS computational biology · 2021Article
- A normalized template matching method for improving spike detection in extracellular voltage recordings.Scientific reports · 2019Article
- Article
- Increased Excitation-Inhibition Ratio Stabilizes Synapse and Circuit Excitability in Four Autism Mouse Models.Neuron · 2019Article
- Whisker-Mediated Touch System in Rodents: From Neuron to Behavior.Frontiers in systems neuroscience · 2019Review
- Biomechanical Texture Coding in Rat Whiskers.Scientific reports · 2018Article
- Article
- Organization of sensory feature selectivity in the whisker system.Neuroscience · 2018Review
- Article
- Transformation of Perception from Sensory to Motor Cortex.Current biology : CB · 2017Article
- Correction: Short Time-Scale Sensory Coding in S1 during Discrimination of Whisker Vibrotactile Sequences.PLoS biology · 2016Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Rodent whisker input consists of dense microvibration sequences that are often temporally integrated for perceptual discrimination. Whether primary somatosensory cortex (S1) participates in temporal integration is unknown. We trained rats to discriminate whisker impulse sequences that varied in single-impulse kinematics (5-20-ms time scale) and mean speed (150-ms time scale). Rats appeared to use the integrated feature, mean speed, to guide discrimination in this task, consistent with similar prior studies. Despite this, 52% of S1 units, including 73% of units in L4 and L2/3, encoded sequences at fast time scales (≤20 ms, mostly 5-10 ms), accurately reflecting single impulse kinematics. 17% of units, mostly in L5, showed weaker impulse responses and a slow firing rate increase during sequences. However, these units did not effectively integrate whisker impulses, but instead combined weak impulse responses with a distinct, slow signal correlated to behavioral choice. A neural decoder could identify sequences from fast unit spike trains and behavioral choice from slow units. Thus, S1 encoded fast time scale whisker input without substantial temporal integration across whisker impulses.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.