Evidence map›Paper›PMID 27574837›Full record

ArticleThe Journal of clinical psychiatry2016

Psychiatric Disorders Among Patients Seeking Treatment for Co-Occurring Chronic Pain and Opioid Use Disorder.

Declan T Barry, Christopher J Cutter, Mark Beitel, Robert D Kerns, Christopher Liong, Richard S Schottenfeld

2 registry-linked trialsAbstract read
In one paragraph

Article in The Journal of clinical psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00634803 phase1 / phase2completednot on this map

Clinical Trial of Integrated Treatment for Pain and Opioid Dependence

TypeinterventionalSponsorYale UniversityRan2009 to 2015Enrolled90ConditionsOpiate Dependence, Chronic PainArmsCBT, Buprenorphine, Educational Counseling, Physician Management
NCT00727675 nacompletednot on this map

Chronic Pain and Opioid Dependence Assessment and Treatment

TypeinterventionalSponsorYale UniversityRan2008 to 2015Enrolled15ConditionsChronic Pain, Opioid DependencyArmsIntegrated Cognitive Behavioral Therapy
3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Declan T BarryYale University School of Medicine, CMHC/SAC Room 220, 34 Park St, New Haven, CT 06519-1187. declan.barry@yale.edu.
Christopher J CutterYale University School of Medicine, New Haven, Connecticut, USA.
Mark BeitelYale University School of Medicine, New Haven, Connecticut, USA.
Robert D KernsYale University School of Medicine, New Haven, Connecticut, USA.
Christopher LiongThe APT Foundation Pain Treatment Services, New Haven, Connecticut, USA.
Richard S SchottenfeldYale University School of Medicine, New Haven, Connecticut, USA.

Funding

Pain and Opioid Dependence (POD)R01DA024695 · NIDA · YALE UNIVERSITY · PI SCHOTTENFELD, RICHARD S · 2009 to 2012
$1.4M
IMPROVING EFFICACY OF DRUG ABUSE TREATMENTK24DA000445 · NIDA · YALE UNIVERSITY · PI SCHOTTENFELD, RICHARD S · 2000 to 2009
$1.3M
Chronic Pain and Opioid Dependence Assessment and TreatmentK23DA024050 · NIDA · YALE UNIVERSITY · PI BARRY, DECLAN T. · 2008 to 2012
$901k
NIDA NIH HHS K23 DA024050NIDA NIH HHS K24 DA000445NIDA NIH HHS R01 DA024695
6 · The paper itself

Abstract

objectivePsychiatric comorbidities complicate treatment of patients with chronic pain and opioid use disorder, but the prevalence of specific comorbid psychiatric disorders in this population has not been systematically investigated.

methods170 consecutive participants entering a treatment research program for co-occurring chronic pain and opioid use disorder between March 2009 and July 2013 were evaluated with the Structured Clinical Interview for DSM-IV-TR Axis I Disorders (SCID-I/P) and the Diagnostic Interview for DSM-IV Personality Disorders (DIPD-IV).

resultsThe prevalence of any lifetime (and current) comorbid Axis I disorder was 91% (75%); 52% met criteria for lifetime anxiety disorder (48% current), 57% for lifetime mood disorder (48% current), and 78% for lifetime nonopioid substance use disorder (34% current). Common current anxiety diagnoses were posttraumatic stress disorder (21%), generalized anxiety disorder (16%), and panic disorder without agoraphobia (16%). Common current mood diagnoses were major depressive disorder (40%) and dysthymia (11%). A majority of patients had a personality disorder (52%).

conclusionsHigh rates and persistence of co-occurring psychiatric disorders, including anxiety or mood disorders, may explain in part the difficulty providers have treating patients with co-occurring opioid use disorder and chronic pain and suggest possible targets for improving treatment.

trial registrationClinicalTrials.gov identifiers: buprenorphine/naloxone treatment (NCT00634803), opioid treatment program-based methadone maintenance treatment (NCT00727675).

Indexed as

AdultBuprenorphineChronic PainComorbidityCross-Sectional StudiesDisability EvaluationFemaleHeroin DependenceHIV SeropositivityHumansIllicit DrugsMaleMental DisordersMethadoneMiddle AgedNaloxoneBuprenorphineIllicit DrugsMethadoneNaloxonePrescription Drugs

Identifiers

PMID27574837
PMCPMC6296217

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.