ArticlePLoS neglected tropical diseases2016
Identification of Tenrec ecaudatus, a Wild Mammal Introduced to Mayotte Island, as a Reservoir of the Newly Identified Human Pathogenic Leptospira mayottensis.
Article in PLoS neglected tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- A systematic review ofOne health (Amsterdam, Netherlands) · 2026Article
- Ticks and tick-borne diseases on southwestern Indian Ocean islands.Parasites & vectors · 2026Review
- Chromosome-level genome assembly of the common tenrec, Tenrec ecaudatus (Schreber, 1778), a new model for early placental mammal evolution.BMC genomics · 2026Article
- Article
- Spatiotemporal dynamics and environmental trends of reported human leptospirosis in Sri Lanka, 2007-2024.Frontiers in public health · 2026Article
- Leptospirosis outbreak in Ecuador in 2023: A pilot study for surveillance from a One Health perspective.One health (Amsterdam, Netherlands) · 2024Article
- Phylogenomics of Leptospira santarosai, a prevalent pathogenic species in the Americas.PLoS neglected tropical diseases · 2023Article
- Clinical manifestations of human leptospirosis: bacteria matter.Frontiers in cellular and infection microbiology · 2023Article
- Reproduction, seasonal morphology, and juvenile growth in three Malagasy fruit bats.Journal of mammalogy · 2022Article
- Co-Radiation ofTropical medicine and infectious disease · 2022Article
- Tracking Animal Reservoirs of PathogenicTropical medicine and infectious disease · 2021Article
- Insight into the Epidemiology of Leptospirosis: A Review ofAnimals : an open access journal from MDPI · 2021Review
- Effects of land use, habitat characteristics, and small mammal community composition on Leptospira prevalence in northeast Madagascar.PLoS neglected tropical diseases · 2020Article
- High frequency of seropositive and carriers of Leptospira spp. in pigs in the semiarid region of northeastern Brazil.Tropical animal health and production · 2020Article
- Isolation and propagation of leptospires at 37 °C directly from the mammalian host.Scientific reports · 2020Article
- Leptospirosis is an invasive infectious and systemic inflammatory disease.Biomedical journal · 2020Review
- Leptospira infection in rats: A literature review of global prevalence and distribution.PLoS neglected tropical diseases · 2019Review
- Genus-wide Leptospira core genome multilocus sequence typing for strain taxonomy and global surveillance.PLoS neglected tropical diseases · 2019Article
- Feral cats do not play a major role in leptospirosis epidemiology on Reunion Island.Epidemiology and infection · 2019Article
- ThreeFrontiers in microbiology · 2019Article
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Authors and funding
10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Leptospirosis is a bacterial zoonosis of major concern on tropical islands. Human populations on western Indian Ocean islands are strongly affected by the disease although each archipelago shows contrasting epidemiology. For instance, Mayotte, part of the Comoros Archipelago, differs from the other neighbouring islands by a high diversity of Leptospira species infecting humans that includes Leptospira mayottensis, a species thought to be unique to this island. Using bacterial culture, molecular detection and typing, the present study explored the wild and domestic local mammalian fauna for renal carriage of leptospires and addressed the genetic relationships of the infecting strains with local isolates obtained from acute human cases and with Leptospira strains hosted by mammal species endemic to nearby Madagascar. Tenrec (Tenrec ecaudatus, Family Tenrecidae), a terrestrial mammal introduced from Madagascar, is identified as a reservoir of L. mayottensis. All isolated L. mayottensis sequence types form a monophyletic clade that includes Leptospira strains infecting humans and tenrecs on Mayotte, as well as two other Malagasy endemic tenrecid species of the genus Microgale. The lower diversity of L. mayottensis in tenrecs from Mayotte, compared to that occurring in Madagascar, suggests that L. mayottensis has indeed a Malagasy origin. This study also showed that introduced rats (Rattus rattus) and dogs are probably the main reservoirs of Leptospira borgpetersenii and Leptospira kirschneri, both bacteria being prevalent in local clinical cases. Data emphasize the epidemiological link between the two neighbouring islands and the role of introduced small mammals in shaping the local epidemiology of leptospirosis.
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