ReviewBurns & trauma2016
A systematic review of objective burn scar measurements.
Review in Burns & trauma, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04736251 (A Prospective Intra-patient Single-blinded Randomised Trial to Examine the Mechanistic Basis of fractiOnal Ablative carbOn Dioxide Laser Therapy in Treating Adult Burns and/or Trauma Patients With Hypertrophic Scarring), which is not on this map. Cited by 67 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Intra-patient Single-blinded Randomised Trial to Examine the Mechanistic Basis of fractiOnal Ablative carbOn Dioxide Laser Therapy in Treating Adult Burns and/or Trauma Patients With Hypertrophic Scarring
Who cites it
67 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- From mechanics to mobilization: a biomechanically-informed rehabilitation framework for cesarean-related scars.BMC women's health · 2026Pooled it
- How to Assess Scar Quality in Pediatric Burn Patients: A Systematic Review on the Type and Content of Outcome Measurement Instruments.Journal of burn care & research : official publication of the American Burn Association · 2025Pooled it
- Combination therapy of pulsed dye laser and ablative fractional carbon dioxide laser for the treatment of pediatric postburn scar: a systematic review.Lasers in medical science · 2025Pooled it
- Pressure-garment therapy for preventing hypertrophic scarring after burn injury.The Cochrane database of systematic reviews · 2024Pooled it
- Devices measuring transepidermal water loss: A systematic review of measurement properties.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2022Pooled it
- Microneedling in the treatment of atrophic scars: A systematic review of randomised controlled trials.International wound journal · 2021Pooled it
- Platelet-rich plasma for striae distensae: What do we know about processed autologous blood contents for treating skin stretchmarks?-A systematic review.International wound journal · 2021Pooled it
- Within-Patient, Evaluator-Blinded, Randomized Controlled Clinical Trial to Assess the Efficacy of Gel Sheets in the Treatment of Hypertrophic Scar in Adult Burn Survivors.Journal of burn care & research : official publication of the American Burn Association · 2026Trial
- Scientific validation of three-dimensional stereophotogrammetry compared to the IGAIS clinical scale for assessing wrinkles and scars after laser treatment.Scientific reports · 2021Trial
- Effectiveness of topical silicone gel and pressure garment therapy for burn scar prevention and management in children: a randomized controlled trial.Clinical rehabilitation · 2020Trial
- Trial
- Efficacy and Safety of Silicone Gel Plus Laser Therapy for Scar: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2026Article
- Within-Patient, Quasi-Experimental Clinical Trial to Assess the Immediate Effects of Paraffin Wax on Adult, Post-Burn Hypertrophic Scar.Journal of burn care & research : official publication of the American Burn Association · 2026Article
- Surgical outcomes of dermabrasion followed by split-thickness skin grafting for post-burn leukoderma: a two-center observational study.BMC surgery · 2026Observational
- Mean human corneal diameter and palpebral fissure lengths as scales for forensic analysis of photographed faces: an analytical review.International journal of legal medicine · 2026Review
- Non-invasive Resonance Raman Spectroscopy provides an early estimation of depth in a pig model of multi-depth burns.Journal of translational medicine · 2025Article
- Evidence Supporting Conservative Scar Management Interventions Following Burn Injury: A Review Article.Journal of burn care & research : official publication of the American Burn Association · 2025Review
- Assessment of the Effect of Kinesiology Taping on Scar Treatment in Children.Clinics and practice · 2025Article
- Review of the 100 Most Cited Articles inEuropean burn journal · 2025Review
- Immediate Changes in the Elasticity of Tissue and the Pain Pressure Threshold in Cesarean Scar Tissue After a Vacuum Intervention: An Open Clinical Trial.Biomedicines · 2025Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundProblematic scarring remains a challenging aspect to address in the treatment of burns and can significantly affect the quality of life of the burn survivor. At present, there are few treatments available in the clinic to control adverse scarring, but experimental pharmacological anti-scarring strategies are now beginning to emerge. Their comparative success must be based on objective measurements of scarring, yet currently the clinical assessment of scars is not carried out systematically and is mostly based on subjective review of patients. However, several techniques and devices are being introduced that allow objective analysis of the burn scar. The aim of this article is to evaluate various objective measurement tools currently available and recommend a useful panel that is suitable for use in clinical trials of anti-scarring therapies.
methodsA systematic literature search was done using the Web of Science, PubMed and Cochrane databases. The identified devices were then classified and grouped according to the parameters they measured. The tools were then compared and assessed in terms of inter- and intra-rater reproducibility, ease of use and cost.
resultsAfter duplicates were removed, 5062 articles were obtained in the search. After further screening, 157 articles which utilised objective burn scar measurement systems or tools were obtained. The scar measurement devices can be broadly classified into those measuring colour, metric variables, texture, biomechanical properties and pathophysiological disturbances.
conclusionsObjective scar measurement tools allow the accurate and reproducible evaluation of scars, which is important for both clinical and scientific use. However, studies to evaluate their relative performance and merits of these tools are scarce, and there remain factors, such as itch and pain, which cannot be measured objectively. On reviewing the available evidence, a panel of devices for objective scar measurement is recommended consisting of the 3D cameras (Eykona/Lifeviz/Vectra H1) for surface area and volume, DSM II colorimeter for colour, Dermascan high-frequency ultrasound for scar thickness and Cutometer for skin elasticity and pliability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.