Evidence map›Paper›PMID 27574674›Full record

ReviewBurns & trauma2016

Endothelial progenitor cells and burn injury - exploring the relationship.

Derek A Banyard, Blake O Adnani, Satenik Melkumyan, Cheryl Ann Araniego, Alan D Widgerow

Abstract readReview
In one paragraph

Review in Burns & trauma, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Deconstructing negative pressure wound therapy.International wound journal · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Derek A BanyardDepartment of Plastic Surgery, Center for Tissue Engineering, University of California, Irvine, 200S Manchester Ave, Ste 650, Orange, CA 92868 USA.
Blake O AdnaniDepartment of Plastic Surgery, Center for Tissue Engineering, University of California, Irvine, 200S Manchester Ave, Ste 650, Orange, CA 92868 USA.
Satenik MelkumyanDepartment of Plastic Surgery, Center for Tissue Engineering, University of California, Irvine, 200S Manchester Ave, Ste 650, Orange, CA 92868 USA.
Cheryl Ann AraniegoDepartment of Plastic Surgery, Center for Tissue Engineering, University of California, Irvine, 200S Manchester Ave, Ste 650, Orange, CA 92868 USA.
Alan D WidgerowDepartment of Plastic Surgery, Center for Tissue Engineering, University of California, Irvine, 200S Manchester Ave, Ste 650, Orange, CA 92868 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Burn wounds result in varying degrees of soft tissue damage that are typically graded clinically. Recently a key participant in neovascularization, the endothelial progenitor cell, has been the subject of intense cardiovascular research to explore whether it can serve as a biomarker for vascular injury. In this review, we examine the identity of the endothelial progenitor cell as well as the evidence that support its role as a key responder after burn insult. While there is conflicting evidence with regards to the delta of endothelial progenitor cell mobilization and burn severity, it is clear that they play an important role in wound healing. Systematic and controlled studies are needed to clarify this relationship, and whether this population can serve as a biomarker for burn severity.

Indexed as

Burn biomarkerBurn depthCirculating angiogenic cellsEndothelial progenitor cells

Identifiers

PMID27574674
PMCPMC4964096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.