Evidence map›Paper›PMID 27574647›Full record

ArticleBurns & trauma2014

History of burns: The past, present and the future.

Kwang Chear Lee, Kavita Joory, Naiem S Moiemen

Registry-linked trialAbstract read
In one paragraph

Article in Burns & trauma, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03520816 (The Effect of Early Physiotherapy on Biochemical Parameters in Major Burn Patients), which is not on this map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03520816 nacompletednot on this mapstarted 2016, after this paper: background citation

The Effect of Early Physiotherapy on Biochemical Parameters in Major Burn Patients: A Burn Center's Experience

TypeinterventionalSponsorHasan Kalyoncu UniversityRan2016 to 2017Enrolled20ConditionsBurns, Physiotherapy, ExercisesArmsBurn Physiotherapy Protocol
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Indications for the use of dermal substitutes in patients with acute burns and in reconstructive surgery after burns: A systematic review.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Pooled it
  2. Review
  3. Review
  4. Burn Selection: How Fire Injury Shaped Human Evolution.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Journal of biomedical optics · 2025
    Article
  10. Article
  11. Review
  12. Review
  13. Pathophysiology of Severe Burn Injuries: New Therapeutic Opportunities From a Systems Perspective.Journal of burn care & research : official publication of the American Burn Association · 2024
    Review
  14. Journal of biomedical optics · 2024
    Article
  15. Article
  16. Early wound excision within three days decreases risks of wound infection and death in burned patients.Burns : journal of the International Society for Burn Injuries · 2023
    Article
  17. Article
  18. Burns: Classification, Pathophysiology, and Treatment: A Review.International journal of molecular sciences · 2023
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kwang Chear LeeThe Healing Foundation Burn Research Centre, University Hospital Birmingham Foundation Trust, Birmingham, UK.
Kavita JooryThe Healing Foundation Burn Research Centre, University Hospital Birmingham Foundation Trust, Birmingham, UK.
Naiem S MoiemenThe Healing Foundation Burn Research Centre, University Hospital Birmingham Foundation Trust, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Burn injuries are one of the most common and devastating afflictions on the human body. In this article we look back at how the treatment of burns has evolved over the centuries from a primarily topical therapy consisting of weird and wonderful topical concoctions in ancient times to one that spans multiple scientific fields of topical therapy, antibiotics, fluid resuscitation, skin excision and grafting, respiratory and metabolic care and nutrition. Most major advances in burn care occurred in the last 50 years, spurred on by wars and great fires. The use of systemic antibiotics and topical silver therapy greatly reduced sepsis related mortality. This along with the advent of antiseptic surgical techniques, burn depth classification and skin grafting allowed the excision and coverage of full-thickness burns which resulted in greatly improved survival rates. Advancements in the methods of assessing the surface area of burns paved way for more accurate fluid resuscitation, minimising the effects of shock and avoiding fluid over-loading. The introduction of metabolic care, nutritional support and care of inhalational injuries further improved the outcome of burn patients. We also briefly discuss some future directions in burn care such as the use of cell and pharmalogical therapies.

Indexed as

Burnsfire disastersfuturehistory

Identifiers

PMID27574647
PMCPMC4978094

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.