ReviewImmune network2016
Regulation of IgE-Mediated Food Allergy by IL-9 Producing Mucosal Mast Cells and Type 2 Innate Lymphoid Cells.
Review in Immune network, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 30 citations in OpenAlex.
- Upregulated Expression of the IL-9 Receptor on TRAF3-Deficient B Lymphocytes Confers Ig Isotype Switching Responsiveness to IL-9 in the Presence of Antigen Receptor Engagement and IL-4.Journal of immunology (Baltimore, Md. : 1950) · 2023Article
- Development of gastro-food allergy model in shrimp allergen extract-induced sensitized mice promotes mast cell degranulation.Journal of public health in Africa · 2023Article
- Bacterial Metabolites: A Link between Gut Microbiota and Dermatological Diseases.International journal of molecular sciences · 2023Review
- The rationale for development of ligelizumab in food allergy.The World Allergy Organization journal · 2022Review
- Editorial: The Role of the Microbiome in Regulating T-Cell Response in Asthma and Food Allergy.Frontiers in immunology · 2021Article
- Crosstalk between the Producers and Immune Targets of IL-9.Immune network · 2020Review
- Exploring the Molecular Mechanisms Underlying the Protective Effects of Microbial SCFAs on Intestinal Tolerance and Food Allergy.Frontiers in immunology · 2020Review
- Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis.JCI insight · 2019Article
- The Initiation of Th2 Immunity Towards Food Allergens.International journal of molecular sciences · 2018Review
- Regulation of Allergic Immune Responses by Microbial Metabolites.Immune network · 2018Review
- Elaeocarpusin Inhibits Mast Cell-Mediated Allergic Inflammation.Frontiers in pharmacology · 2018Article
- Diospyros kaki calyx inhibits immediate-type hypersensitivity via the reduction of mast cell activation.Pharmaceutical biology · 2017Article
- Beyond Hygiene: Commensal Microbiota and Allergic Diseases.Immune network · 2017Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to the increasing prevalence and number of life-threatening cases, food allergy has emerged as a major health concern. The classic immune response seen during food allergy is allergen-specific IgE sensitization and hypersensitivity reactions to foods occur in the effector phase with often severe and deleterious outcomes. Recent research has advanced understanding of the immunological mechanisms occurring during the effector phase of allergic reactions to ingested food. Therefore, this review will not only cover the mucosal immune system of the gastrointestinal tract and the immunological mechanisms underlying IgE-mediated food allergy, but will also introduce cells recently identified to have a role in the hypersensitivity reaction to food allergens. These include IL-9 producing mucosal mast cells (MMC9s) and type 2 innate lymphoid cells (ILC2s). The involvement of these cell types in potentiating the type 2 immune response and developing the anaphylactic response to food allergens will be discussed. In addition, it has become apparent that there is a collaboration between these cells that contributes to an individual's susceptibility to IgE-mediated food allergy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.