ArticleAnnals of surgery1989
Influence of site of origin and mucin production on survival in ampullary carcinoma.
Article in Annals of surgery, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 33 citations in OpenAlex.
- The future of adjuvant therapy in ampullary cancer: should we offer it to our patients?Hepatobiliary surgery and nutrition · 2020Article
- Signet-ring cell carcinoma of the distal common bile duct: report of a case.Korean journal of pathology · 2014Article
- Prognostic factors for ampullary adenocarcinomas: tumor stage, tumor histology, tumor location, immunohistochemistry and microsatellite instability.Virchows Archiv : an international journal of pathology · 2007Article
- Carcinoma of the ampulla of Vater: prognostic factors after curative surgery: a series of 45 cases.Gut · 1997Article
- Neoplasia of the ampulla of Vater. Ki-ras and p53 mutations.The American journal of pathology · 1993Article
- Human cell line from an adenocarcinoma of the ampulla of Vater.In vitro cellular & developmental biology : journal of the Tissue Culture Association · 1992Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We studied a series of 26 cases of carcinoma of the ampulla of Vater. There were 24 adenocarcinomas and two neuroendocrine tumors. Histologically the carcinomas could be divided into tumors arising from periampullary duodenal mucosa and those arising within the ampulla. True ampullary tumors had a significantly better 5-year survival rate (p = 0.028) than periampullary tumors. The type of mucin produced was investigated histochemically. Patients with true ampullary tumors producing predominantly sialomucins had a better prognosis than those with tumors secreting sulphated mucins (p = 0.045), but the numbers were small. We hypothesize that the most favorable type of ampullary carcinoma arises from biliary-type epithelium within the ampulla.
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Registered trials
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