ArticleScientific reports2016
MicroRNA393 is involved in nitrogen-promoted rice tillering through regulation of auxin signal transduction in axillary buds.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33 citing papers in PubMed, 81 citations in OpenAlex.
- Copper-sensitive OsSPL9 TF regulates expression of indica rice domestication-associated miRNAs and phenotypes.Communications biology · 2026Article
- Rice and shine: a review of miRNA-mediated responses to abiotic stress inFrontiers in plant science · 2026Review
- Genome-Wide Association Studies Identify OsNLP6 as a Key Regulator of Nitrogen Use Efficiency in Rice.Plant biotechnology journal · 2025Article
- Adaptive dynamics of extrachromosomal circular DNA in rice under nutrient stress.Nature communications · 2025Article
- Sugar Transport and Signaling in Shoot Branching.International journal of molecular sciences · 2024Review
- Genome-Wide Association Analysis of Effective Tillers in Rice under Different Nitrogen Gradients.International journal of molecular sciences · 2024Article
- Unlocking the Multifaceted Mechanisms of Bud Outgrowth: Advances in Understanding Shoot Branching.Plants (Basel, Switzerland) · 2023Review
- miRNA mediated regulation of nitrogen response and nitrogen use efficiency of plants: the case of wheat.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Genetic basis controlling rice plant architecture and its modification for breeding.Breeding science · 2023Article
- Unlocking the potentials of nitrate transporters at improving plant nitrogen use efficiency.Frontiers in plant science · 2023Review
- Relationship between reduction in rice (Nipponbare) leaf blade size under elevated COPlant signaling & behavior · 2022Article
- Breeding for Higher Yields of Wheat and Rice through Modifying Nitrogen Metabolism.Plants (Basel, Switzerland) · 2022Review
- Nitrate signaling and use efficiency in crops.Plant communications · 2022Review
- The miR393-Target Module Regulates Plant Development and Responses to Biotic and Abiotic Stresses.International journal of molecular sciences · 2022Review
- Osa-miR1320 targets the ERF transcription factor OsERF096 to regulate cold tolerance via JA-mediated signaling.Plant physiology · 2022Article
- Degradome sequencing reveals an integrative miRNA-mediated gene interaction network regulating rice seed vigor.BMC plant biology · 2022Article
- Analysis of miRNAs responsive to long-term calcium deficiency in tef (Plant direct · 2022Article
- MicroRNA Mediated Plant Responses to Nutrient Stress.International journal of molecular sciences · 2022Review
- The role of auxin in nitrogen-modulated shoot branching.Plant signaling & behavior · 2021Review
- Photocontrol of Axillary Bud Outgrowth by MicroRNAs: Current State-of-the-Art and Novel Perspectives Gained From the Rosebush Model.Frontiers in plant science · 2021Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rice tillering has an important influence on grain yield, and is promoted by nitrogen (N) fertilizer. Several genes controlling rice tillering, which are regulated by poor N supply, have been identified. However, the molecular mechanism associated with the regulation of tillering based on N supply is poorly understood. Here, we report that rice microRNA393 (OsmiR393) is involved in N-mediated tillering by decreasing auxin signal sensitivity in axillary buds. Expression analysis showed that N fertilizer causes up-regulation of OsmiR393, but down-regulation of two target genes (OsAFB2 and OsTB1). In situ expression analysis showed that OsmiR393 is highly expressed in the lateral axillary meristem. OsmiR393 overexpression mimicked N-mediated tillering in wild type Zhonghua 11 (ZH11). Mutation of OsMIR393 in ZH11 repressed N-promoted tillering, which simulated the effects of limited N, and this could not be restored by supplying N fertilizer. Western blot analysis showed that OsIAA6 was accumulated in both OsmiR393-overexpressing lines and N-treated wild type rice, but was reduced in the OsMIR393 mutant. Therefore, we deduced that N-induced OsmiR393 accumulation reduces the expression of OsTIR1 and OsAFB2, which alleviates sensitivity to auxin in the axillary buds and stabilizes OsIAA6, thereby promoting rice tillering.
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