ArticleAnnals of surgical oncology2017
The DISINFECT Initiative: Decreasing the Incidence of Surgical INFECTions in Gynecologic Oncology.
Article in Annals of surgical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Economic Evaluations Informed Exclusively by Real World Data: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Surgical treatment and prognosis in patients with intestinal metastases originated from advanced epithelial ovarian cancer.Frontiers in oncology · 2026Article
- Metronidazole and cefazolin vs cefazolin alone for surgical site infection prophylaxis in gynecologic surgery at a comprehensive cancer center.American journal of obstetrics and gynecology · 2024Article
- A combination of laparoscopic approach and ERAS pathway optimizes outcomes and cost for adrenalectomy.Updates in surgery · 2022Article
- Expert commentary on the challenges and opportunities for surgical site infection prevention through implementation of evidence-based guidelines in the Asia-Pacific Region.Antimicrobial resistance and infection control · 2021Article
- Enhanced recovery for obese patients undergoing gynecologic cancer surgery.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2020Observational
- Urinary tract infection after clean-contaminated pelvic surgery: a retrospective cohort study and prediction model.International urogynecology journal · 2020Article
- Choosing Wisely: Decreasing the incidence of perioperative blood transfusions in gynecologic oncology.Gynecologic oncology · 2019Article
- Enhanced recovery after surgery: implementing a new standard of surgical care.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2019Review
Corrections and comments
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundSurgical site infections (SSIs) lead to increased patient morbidity and healthcare costs. Our objective was to decrease the SSI rate following gynecologic surgery.
methodsAdult patients undergoing abdominal surgery for gynecologic malignancy or benign disease received the following: patient education; preoperative antibacterial soap; appropriate antibiotic prophylaxis; change of gloves and use of clean instruments at surgical closure; surgical dressing for 48 h; and a post-discharge phone call. The baseline SSI rate was determined retrospectively (1 April 2014-30 June 2014), while the post-intervention SSI rate was determined prospectively (16 February 2015-15 October 2015). The main outcome was the overall SSI rate with secondary outcomes, including the rate of superficial, deep, incisional and organ space infection, as well as the cost effectiveness of the bundle.
resultsA total of 232 baseline and 555 post-intervention patients were included in the study. No differences were observed between the baseline and post-intervention groups with regard to median body mass index (BMI), surgical approach, receipt of preoperative chemotherapy and/or radiation therapy, and cases including bowel surgery. Overall, the SSI rate decreased significantly from baseline [12.5 %] to post-intervention [7.4 %] (odds ratio [OR] 0.56, 90 % confidence interval [CI] 0.37-0.85; p = 0.01). A 40 % decrease was noted in the rate of superficial and deep infections (9.5 vs. 5.9 %; OR 0.60, 90 % CI 0.38-0.97; p = 0.04) and SSIs after open surgery (21.4 vs. 13.2 %; OR 0.56, 90 % CI 0.34-0.92; p = 0.03). The estimated cost of the intervention was $19.26/case and the net total amount saved during the post-intervention period was $65,625 month.
conclusionsThis bundled intervention led to a significant decrease in the overall SSI rate and was cost effective. The largest decreases in SSIs were in incisional infections and following open surgery.
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