ArticleThe Journal of biological chemistry2016
Pharmacological Correction of Trafficking Defects in ATP-sensitive Potassium Channels Caused by Sulfonylurea Receptor 1 Mutations.
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Article in The Journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
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Who cites it
28 citing papers in PubMed, 51 citations in OpenAlex.
- Identification and rescue of congenital hyperinsulinism-associated ABCC8 mutations that impair KThe Journal of biological chemistry · 2025Article
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- Non-radioactive RbMethods in molecular biology (Clifton, N.J.) · 2024Article
- KFrontiers in endocrinology · 2023Review
- Applications of genetic code expansion and photosensitive UAAs in studying membrane proteins.Open life sciences · 2023Review
- Maturity-Onset Diabetes of the Young: Mutations, Physiological Consequences, and Treatment Options.Journal of personalized medicine · 2022Review
- Subcellular trafficking and endocytic recycling of KAmerican journal of physiology. Cell physiology · 2022Review
- Carbamazepine promotes surface expression of mutant Kir6.2-A28V ATP-sensitive potassium channels by modulating Golgi retention and autophagy.The Journal of biological chemistry · 2022Article
- A High-Throughput Screening Assay to Identify Drugs that Can Treat Long QT Syndrome Caused by Trafficking-Deficient KMolecular pharmacology · 2022Article
- A case report of Maturity-onset diabetes of the young 12: large fragment deletion inAnnals of translational medicine · 2022Article
- Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes.Nature communications · 2022Article
- High-throughput characterization of photocrosslinker-bearing ion channel variants to map residues critical for function and pharmacology.PLoS biology · 2021Article
- Production and purification of ATP-sensitive potassium channel particles for cryo-electron microscopy.Methods in enzymology · 2021Article
- Hyperinsulinemic hypoglycemia in children and adolescents: Recent advances in understanding of pathophysiology and management.Reviews in endocrine & metabolic disorders · 2020Review
- Identification of a compound heterozygous inactivating ABCC8 gene mutation responsible for young-onset diabetes with exome sequencing.Journal of diabetes investigation · 2020Article
- Pharmacological chaperones of ATP-sensitive potassium channels: Mechanistic insight from cryoEM structures.Molecular and cellular endocrinology · 2020Review
- Novel dominant KAmerican journal of medical genetics. Part A · 2019Article
- Article
- Gating modules of the AMPA receptor pore domain revealed by unnatural amino acid mutagenesis.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Functional characterization of activating mutations in the sulfonylurea receptor 1 (ABCC8) causing neonatal diabetes mellitus in Asian Indian children.Pediatric diabetes · 2019Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Gregory M MartinFrom the Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon 97239.
Emily A RexFrom the Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon 97239.
Prasanna DevaraneniFrom the Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon 97239.
Jerod S Dentonthe Department of Anesthesiology, Vanderbilt University, Nashville, Tennessee 37232, and.
Kara E Boodhansinghthe Division of Endocrinology/Diabetes, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104.
Diva D DeLeonthe Division of Endocrinology/Diabetes, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104.
Charles A Stanleythe Division of Endocrinology/Diabetes, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104.
Show-Ling ShyngFrom the Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon 97239, shyngs@ohsu.edu.
Oregon Health & Science University · USChildren's Hospital of Philadelphia · USVanderbilt University · US
Funding
KATP channels and insulin secretionR01DK057699 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI SHYNG, SHOW-LING · 2001 to 2019
$6.1MIslet Dysregulation in Infants with Congenital HyperinsulinismR37DK056268 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI STANLEY, CHARLES ALFRED · 2009 to 2017
$6.0MStructural Basis of KATP Channel GatingR01DK066485 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI SHYNG, SHOW-LING · 2006 to 2024
$5.8MInsulin Secretion in Hyperinsulinism Human IsletsR01DK098517 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI DE LEON, DIVA D. · 2013 to 2023
$4.5MProgram in Molecular and Cellular BiosciencesT32GM071338 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI MASLEN, CHERYL L · 2005 to 2020
$3.5MPharmacological rescue of trafficking-impaired KATP channelsF31DK105800 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI MARTIN, GREGORY M · 2015 to 2017
$131kNIDDK NIH HHS F31 DK105800NIDDK NIH HHS R01 DK057699NIDDK NIH HHS R01 DK066485NIDDK NIH HHS R01 DK098517NIDDK NIH HHS R37 DK056268NIGMS NIH HHS T32 GM071338
Abstract
ATP-sensitive potassium (K
Indexed as
MutationCarbamazepineFemaleGlyburideHumansKcnj11 ChannelMalePotassium Channels, Inwardly RectifyingProtein TransportSulfonylurea CompoundsSulfonylurea ReceptorsABCC8 protein, humanCarbamazepineGlyburideKcnj11 ChannelPotassium Channels, Inwardly RectifyingSulfonylurea CompoundsSulfonylurea ReceptorsABC transporterATP-binding cassette transporter subfamily C member 8 (ABCC8)chaperonegatinghypoglycemiainsulin secretionintracellular traffickingpotassium channelprotein misfoldingprotein processing
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.